GAD65 anticorps (C-Term)
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- Antigène Voir toutes GAD65 (GAD2) Anticorps
- GAD65 (GAD2) (Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2))
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GAD65 est non-conjugé
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Application
- Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificité
- This antibody is specific for GAD65 protein, and it does not cross-react with GAD67 protein.
- Réactivité croisée
- Humain, Souris, Rat
- Attributs du produit
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Rabbit Polyclonal antibody to GAD65 (glutamate decarboxylase 2 (pancreatic islets and brain, 65 kDa))
GAD65 antibody [C2C3], C-term - Purification
- Purified by antigen-affinity chromatography.
- Immunogène
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human GAD65. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product GAD2 Anticorps primaire
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- Indications d'application
- WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Commentaires
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Positive Control: mouse brain , rat brain
Validation: Overexpression
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
- Agent conservateur
- Thimerosal (Merthiolate)
- Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Antigène
- GAD65 (GAD2) (Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2))
- Autre désignation
- glutamate decarboxylase 2 (GAD2 Produits)
- Synonymes
- anticorps GAD65, anticorps gad65, anticorps F12P19.12, anticorps F12P19_12, anticorps GLUTAMATE DECARBOXYLASE 2, anticorps glutamate decarboxylase 2, anticorps zgc:112198, anticorps 6330404F12Rik, anticorps GAD(65), anticorps Gad-2, anticorps glutamate decarboxylase 2, anticorps glutamate decarboxylase 1, anticorps glutamic acid decarboxylase 2, anticorps GAD2, anticorps PTRG_06148, anticorps LOC9324534, anticorps Gad2, anticorps GAD1, anticorps gad2
- Sujet
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This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
Cellular Localization: Cytoplasm , cytosol , Cytoplasmic vesicle , Cell junction , synapse , presynaptic cell membrane , Golgi apparatus membrane - Poids moléculaire
- 65 kDa
- ID gène
- 2572
- UniProt
- Q05329
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