PDIA3 anticorps (C-Term)

N° du produit ABIN2854699

Détail du produit anti-PDIA3 anticorps

Antigène: PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDIA3 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Rabbit Polyclonal antibody to ERp57 (protein disulfide isomerase family A, member 3)
ERp57 antibody [C3], C-term

Purification: Affinity purified by Protein A.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ERp57. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: NIH-3T3 , JC , BCL-1 , H1299 , HeLa , HepG2

Validation: Comparison

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur PDIA3

Antigène: PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))

Autre désignation: protein disulfide isomerase family A member 3 (PDIA3 Produits)

Synonymes: anticorps ER60, anticorps ERp57, anticorps ERp60, anticorps ERp61, anticorps GRP57, anticorps GRP58, anticorps HsT17083, anticorps P58, anticorps PI-PLC, anticorps grp-58, anticorps 58kDa, anticorps Erp, anticorps Grp58, anticorps PDI, anticorps PDI-Q2, anticorps PLC[a], anticorps Plca, anticorps 1, anticorps 25D3-membrane-associated, anticorps sb:cb825, anticorps erp57, anticorps grp58, anticorps pdia3, anticorps protein disulfide isomerase family A member 3, anticorps protein disulfide-isomerase A3, anticorps protein disulfide isomerase associated 3, anticorps protein disulfide isomerase family A, member 3, anticorps protein disulfide isomerase family A member 3 S homeolog, anticorps PDIA3, anticorps Tsp_10062, anticorps Pdia3, anticorps pdia3, anticorps pdia3.S

Sujet: This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase, however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.

Cellular Localization: Endoplasmic reticulum lumen (By similarity) , Melanosome

Poids moléculaire: 57 kDa

ID gène: 2923

UniProt: P30101

Pathways: Maintenance of Protein Location, Protein targeting to Nucleus, Cell RedoxHomeostasis