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ADRA2C anticorps (C-Term)

ADRA2C Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2854717
  • Antigène Voir toutes ADRA2C Anticorps
    ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))
    Épitope
    • 23
    • 23
    • 16
    • 10
    • 8
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 82
    • 47
    • 20
    • 7
    • 4
    • 4
    • 2
    • 1
    Humain
    Hôte
    • 59
    • 26
    Lapin
    Clonalité
    • 59
    • 26
    Polyclonal
    Conjugué
    • 31
    • 6
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ADRA2C est non-conjugé
    Application
    • 55
    • 25
    • 20
    • 17
    • 15
    • 14
    • 13
    • 13
    • 11
    • 11
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain
    Attributs du produit
    Rabbit Polyclonal antibody to alpha 2c Adrenergic Receptor (adrenergic, alpha-2C-, receptor)
    alpha 2c Adrenergic Receptor antibody [C2C3], C-term
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human alpha 2c Adrenergic Receptor. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product ADRA2C Anticorps primaire
  • Indications d'application
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Commentaires

    Positive Control: HeLa

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.62 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Agent conservateur
    Thimerosal (Merthiolate)
    Précaution d'utilisation
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))
    Autre désignation
    adrenoceptor alpha 2C (ADRA2C Produits)
    Synonymes
    anticorps ADRA2L2, anticorps ADRA2RL2, anticorps ADRARL2, anticorps ALPHA2CAR, anticorps Adra-2c, anticorps [a]2C, anticorps alpha2-C4, anticorps alpha2C, anticorps zgc:194523, anticorps zgc:194541, anticorps adra2c, anticorps ADRA2B, anticorps ADRA2C, anticorps adrenoceptor alpha 2C, anticorps adrenergic receptor, alpha 2c, anticorps ADRA2C, anticorps Adra2c, anticorps adra2c
    Sujet
    Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences.

    Cellular Localization: Cell membrane
    Poids moléculaire
    50 kDa
    ID gène
    152
    UniProt
    P18825
    Pathways
    EGFR Signaling Pathway, cAMP Metabolic Process
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