CXCR5 anticorps

N° du produit ABIN2854723

Détail du produit anti-CXCR5 anticorps

Antigène: CXCR5 (Chemokine (C-X-C Motif) Receptor 5 (CXCR5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CXCR5 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Réactivité croisée: Humain, Souris

Attributs du produit: Rabbit Polyclonal antibody to CXCR5 (chemokine (C-X-C motif) receptor 5)
CXCR5 antibody [C1C2], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human CXCR5. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: HepG2

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 40 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-CXCR5 (ABIN2854723)

Lin, Izar, Wang, Yapp, Mei, Shah, Santagata, Sorger: "Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes." dans: eLife, Vol. 7, (2019) (PubMed).

Yang, Wei, Liu, Shi, Li: "Frequency and distribution of CD4+CXCR5+ follicular B helper T cells within involved tissues in IgG4‑related ophthalmic disease." dans: Molecular medicine reports, Vol. 16, Issue 6, pp. 9512-9520, (2018) (PubMed).

Détails sur CXCR5

Antigène: CXCR5 (Chemokine (C-X-C Motif) Receptor 5 (CXCR5))

Autre désignation: C-X-C motif chemokine receptor 5 (CXCR5 Produits)

Synonymes: anticorps BLR1, anticorps CRL1, anticorps CD185, anticorps MDR15, anticorps Blr1, anticorps CXC-R5, anticorps CXCR-5, anticorps Gpcr6, anticorps NLR, anticorps C-X-C motif chemokine receptor 5, anticorps chemokine (C-X-C motif) receptor 5, anticorps CXCR5, anticorps Cxcr5

Sujet: This gene was identified as a gene specifically expressed in Burkitt's lymphoma and lymphatic tissues. The protein encoded by this gene is predicted to be a seven transmembrane G protein- coupled receptor and belongs to the CXC chemokine receptor family. BLC, a B-lymphocyte chemoattractant, was identified to be a specific ligand for this receptor. Studies of this gene and its mouse conterpart strongly suggest the essential function of this gene in B cell migration and localization within specific anatomic compartments, such as follicles in lymph nodes as well as in spleen. Two alternatively spliced variants of this gene exist.

Cellular Localization: Cell membrane

Poids moléculaire: 42 kDa

ID gène: 643

UniProt: P32302