HRH4 anticorps (N-Term)

N° du produit ABIN2854739

Détail du produit anti-HRH4 anticorps

Antigène: HRH4 (Histamine Receptor H4 (HRH4))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HRH4 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Humain

Attributs du produit: Rabbit polyclonal antibody to Histamine H4 Receptor (histamine receptor H4)
Histamine H4 Receptor antibody [N1N2], N-term

Purification: Purified by antigen-affinity chromatography.

Classe de qualité: KO Validated

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Histamine H4 Receptor. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: Jurkat , Raji , NCI-H929 , human shHRH4-transfected HeLa cells

Validation: KO/KD

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 50 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-HRH4 (ABIN2854739)

Adderley, Zhang, Breslin: "Involvement of the H1 Histamine Receptor, p38 MAP Kinase, Myosin Light Chains Kinase, and Rho/ROCK in Histamine-Induced Endothelial Barrier Dysfunction." dans: Microcirculation (New York, N.Y. : 1994), Vol. 22, Issue 4, pp. 237-48, (2016) (PubMed).

Détails sur HRH4

Antigène: HRH4 (Histamine Receptor H4 (HRH4))

Autre désignation: histamine receptor H4 (HRH4 Produits)

Sujet: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H4 belongs to the family 1 of G protein-coupled receptors and has the highest homology to histamine receptor H3 among known G protein-coupled receptors.

Cellular Localization: Cell membrane, Multi-pass membrane protein

Poids moléculaire: 44 kDa

ID gène: 59340

UniProt: Q9H3N8