CXCR1 anticorps (C-Term)
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- Antigène Voir toutes CXCR1 Anticorps
- CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CXCR1 est non-conjugé
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Réactivité croisée
- Humain, Souris
- Attributs du produit
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Rabbit Polyclonal antibody to CXCR1 (chemokine (C-X-C motif) receptor 1)
CXCR1 antibody [C2C3], C-term - Purification
- Purified by antigen-affinity chromatography.
- Classe de qualité
- KO Validated
- Immunogène
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CXCR1. The exact sequence is proprietary.
- Isotype
- IgG
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- Indications d'application
- ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Commentaires
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Validation: KO/KD
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.97 mg/mL
- Buffer
- 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Antigène
- CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))
- Autre désignation
- C-X-C motif chemokine receptor 1 (CXCR1 Produits)
- Synonymes
- anticorps C-C, anticorps C-C-CKR-1, anticorps CD128, anticorps CD181, anticorps CDw128a, anticorps CKR-1, anticorps CMKAR1, anticorps IL8R1, anticorps IL8RA, anticorps IL8RBA, anticorps Il8ra, anticorps CXCR-1, anticorps IL-8RA, anticorps CXCR2, anticorps IL8RB, anticorps cxcr1, anticorps cxcr2, anticorps C-X-C motif chemokine receptor 1, anticorps chemokine (C-X-C motif) receptor 1, anticorps C-X-C chemokine receptor type 1, anticorps C-X-C motif chemokine receptor 1 S homeolog, anticorps CXCR1, anticorps Cxcr1, anticorps LOC100461947, anticorps cxcr1.S
- Sujet
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The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.
Cellular Localization: Cell membrane - Poids moléculaire
- 40 kDa
- ID gène
- 3577
- UniProt
- P25024
- Pathways
- cAMP Metabolic Process
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