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CXCR1 anticorps (C-Term)

KO Validated CXCR1 Reactivité: Humain IHC (p), ICC, IF, IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2854740
  • Antigène Voir toutes CXCR1 Anticorps
    CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))
    Épitope
    • 15
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 49
    • 17
    • 10
    Humain
    Hôte
    • 40
    • 11
    • 5
    Lapin
    Clonalité
    • 44
    • 11
    • 1
    Polyclonal
    Conjugué
    • 24
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CXCR1 est non-conjugé
    Application
    • 35
    • 20
    • 13
    • 13
    • 12
    • 11
    • 11
    • 9
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Humain, Souris
    Attributs du produit
    Rabbit Polyclonal antibody to CXCR1 (chemokine (C-X-C motif) receptor 1)
    CXCR1 antibody [C2C3], C-term
    Purification
    Purified by antigen-affinity chromatography.
    Classe de qualité
    KO Validated
    Immunogène
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CXCR1. The exact sequence is proprietary.
    Isotype
    IgG
  • Indications d'application
    ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Commentaires

    Validation: KO/KD

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.97 mg/mL
    Buffer
    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))
    Autre désignation
    C-X-C motif chemokine receptor 1 (CXCR1 Produits)
    Synonymes
    anticorps C-C, anticorps C-C-CKR-1, anticorps CD128, anticorps CD181, anticorps CDw128a, anticorps CKR-1, anticorps CMKAR1, anticorps IL8R1, anticorps IL8RA, anticorps IL8RBA, anticorps Il8ra, anticorps CXCR-1, anticorps IL-8RA, anticorps CXCR2, anticorps IL8RB, anticorps cxcr1, anticorps cxcr2, anticorps C-X-C motif chemokine receptor 1, anticorps chemokine (C-X-C motif) receptor 1, anticorps C-X-C chemokine receptor type 1, anticorps C-X-C motif chemokine receptor 1 S homeolog, anticorps CXCR1, anticorps Cxcr1, anticorps LOC100461947, anticorps cxcr1.S
    Sujet
    The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.

    Cellular Localization: Cell membrane
    Poids moléculaire
    40 kDa
    ID gène
    3577
    UniProt
    P25024
    Pathways
    cAMP Metabolic Process
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