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POLG anticorps (C-Term)

POLG Reactivité: Humain WB, IHC (p), IF, ICC, IP Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2854742
  • Antigène Voir toutes POLG Anticorps
    POLG (Polymerase (DNA Directed), gamma (POLG))
    Épitope
    • 15
    • 9
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 52
    • 27
    • 24
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 52
    • 2
    Lapin
    Clonalité
    • 51
    • 3
    Polyclonal
    Conjugué
    • 19
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp POLG est non-conjugé
    Application
    • 37
    • 15
    • 13
    • 13
    • 10
    • 10
    • 7
    • 7
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP)
     Réactivité croisée
    Humain, Rat
    Attributs du produit
    Rabbit Polyclonal antibody to DNA polymerase gamma (polymerase (DNA directed), gamma)
    DNA polymerase gamma antibody
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Recombinant protein encompassing a sequence within the C-terminus region of human DNA polymerase gamma. The exact sequence is proprietary.
    Isotype
    IgG
  • Indications d'application
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Commentaires

    Positive Control: Rat testis , MCF-7 , MDA-MB-231

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.67 mg/mL
    Buffer
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    POLG (Polymerase (DNA Directed), gamma (POLG))
    Autre désignation
    DNA polymerase gamma (POLG Produits)
    Synonymes
    anticorps POLG, anticorps MDP1, anticorps MIRAS, anticorps MTDPS4A, anticorps MTDPS4B, anticorps PEO, anticorps POLG1, anticorps POLGA, anticorps SANDO, anticorps SCAE, anticorps AA409516, anticorps PolgA, anticorps polymerase (DNA) gamma, catalytic subunit L homeolog, anticorps DNA polymerase gamma, catalytic subunit, anticorps polymerase (DNA directed), gamma, anticorps polg.L, anticorps Polg, anticorps POLG, anticorps polg
    Classe de substances
    Viral Protein
    Sujet
    Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene.

    Cellular Localization: Mitochondrion
    Poids moléculaire
    140 kDa
    ID gène
    5428
    UniProt
    P54098
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