RHOC anticorps

N° du produit ABIN2854791

Détail du produit anti-RHOC anticorps

Antigène: RHOC (Ras Homolog Gene Family, Member C (RHOC))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RHOC est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Réactivité croisée: Humain, Souris

Attributs du produit: Rabbit Polyclonal antibody to RhoC (ras homolog gene family, member C)
RhoC antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human RhoC. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: A431 , Mouse liver

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur RHOC

Antigène: RHOC (Ras Homolog Gene Family, Member C (RHOC))

Autre désignation: ras homolog family member C (RHOC Produits)

Synonymes: anticorps ARHC, anticorps LOC100221682, anticorps ARH9, anticorps H9, anticorps RHOH9, anticorps AI324259, anticorps Arh9, anticorps Arhc, anticorps CRHOC, anticorps ras homolog family member C L homeolog, anticorps ras homolog family member C, anticorps rhoc.L, anticorps RHOC, anticorps rhoc, anticorps Rhoc

Sujet: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Cellular Localization: Cell membrane, Lipid-anchor, Cytoplasmic side

Poids moléculaire: 22 kDa

ID gène: 389

UniProt: P08134

Pathways: Signalisation WNT, Cell-Cell Junction Organization