SOD1 anticorps

N° du produit ABIN2854793

Détail du produit anti-SOD1 anticorps

Antigène: SOD1 (Superoxide Dismutase 1, Soluble (SOD1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOD1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Alligator, Avian, Humain, Souris, Rat

Attributs du produit: Rabbit Polyclonal antibody to SOD1 (superoxide dismutase 1, soluble)
SOD1 antibody

Purification: Purified by antigen-affinity chromatography.

Classe de qualité: KO Validated

Immunogène: Recombinant protein encompassing a sequence within the center region of human SOD1. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:10000. IHC-P: 1:100-1:1000. ELISA: 1:1000-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: mouse brain , Rat brain , NT2D1 , 293T

Validation: KO/KD, Orthogonal

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.15 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-SOD1 (ABIN2854793)

Balhorn, Hartmann, Schupp: "Aldosterone Induces DNA Damage and Activation of Nrf2 Mainly in Tubuli of Mouse Kidneys." dans: International journal of molecular sciences, Vol. 21, Issue 13, (2020) (PubMed).

Parry, Kephart, Mumford, Romero, Mobley, Zhang, Roberts, Kavazis: "Ketogenic diet increases mitochondria volume in the liver and skeletal muscle without altering oxidative stress markers in rats." dans: Heliyon, Vol. 4, Issue 11, pp. e00975, (2018) (PubMed).

Gentile, Fornai, Pellegrini, Colucci, Benvenuti, Duranti, Masi, Carpi, Nieri, Nericcio, Garelli, Virdis, Pistelli, Blandizzi, Antonioli: "Luteolin Prevents Cardiometabolic Alterations and Vascular Dysfunction in Mice With HFD-Induced Obesity." dans: Frontiers in pharmacology, Vol. 9, pp. 1094, (2018) (PubMed).

Mowry, Kavazis, Sirman, Potts, Hood: "Reproduction Does Not Adversely Affect Liver Mitochondrial Respiratory Function but Results in Lipid Peroxidation and Increased Antioxidants in House Mice." dans: PLoS ONE, Vol. 11, Issue 8, pp. e0160883, (2017) (PubMed).

Brand, Amann, Mandel, Zimnol, Schupp: "Oxidative DNA damage in kidneys and heart of hypertensive mice is prevented by blocking angiotensin II and aldosterone receptors." dans: PLoS ONE, Vol. 9, Issue 12, pp. e115715, (2015) (PubMed).

Détails sur SOD1

Antigène: SOD1 (Superoxide Dismutase 1, Soluble (SOD1))

Autre désignation: superoxide dismutase 1 (SOD1 Produits)

Synonymes: anticorps LOC692639, anticorps ALS, anticorps ALS1, anticorps IPOA, anticorps SOD, anticorps hSod1, anticorps homodimer, anticorps CG11793, anticorps Cu, anticorps Cu-Zn SOD, anticorps Cu/Zn SOD, anticorps Cu/Zn sod, anticorps Cu/Zn superoxide dismutase, anticorps Cu/ZnSOD, anticorps CuSOD, anticorps CuZn SOD, anticorps CuZn-SOD, anticorps CuZn-SOD1, anticorps CuZnSOD, anticorps Cu[2+]/Zn[2+]SOD, anticorps Dmel\\CG11793, anticorps G, anticorps Mn SOD, anticorps SOD-1, anticorps SOD1, anticorps Sod-1, anticorps Sod1, anticorps To, anticorps To-1, anticorps Zn SOD, anticorps Zn Sod, anticorps Zn-SOD, anticorps ZnSod, anticorps cSOD, anticorps cSod, anticorps dSOD1, anticorps l(3)108, anticorps l(3)68Af', anticorps l(3)G, anticorps sod, anticorps sod1, anticorps CU/ZN-SOD, anticorps SODC, anticorps DKFZP469M1833, anticorps B430204E11Rik, anticorps Cu/Zn-SOD, anticorps Ipo-1, anticorps Ipo1, anticorps SOD1L1, anticorps XSODB, anticorps als, anticorps als1, anticorps ipoa, anticorps sod1-a, anticorps ZSOD, anticorps cuzn, anticorps Cu/Zn superoxide dismutase, anticorps superoxide dismutase 1, anticorps Superoxide dismutase 1, anticorps superoxide dismutase 1, soluble, anticorps superoxide dismutase 1 S homeolog, anticorps Superoxide dismutase [Cu-Zn], anticorps superoxide dismutase 1 L homeolog, anticorps superoxide dismutase [Cu-Zn]-like, anticorps superoxide dismutase [Cu-Zn], anticorps superoxide dismutase Sod1, anticorps SOD, anticorps SOD1, anticorps Sod1, anticorps sod1, anticorps sod1.S, anticorps sod-1, anticorps sod1.L, anticorps LOC101451855, anticorps LOC101115136

Sujet: The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.

Cellular Localization: Cytoplasm

Poids moléculaire: 16 kDa

ID gène: 6647

UniProt: P00441

Pathways: Sensory Perception of Sound, Transition Metal Ion Homeostasis