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MTDH anticorps

MTDH Reactivité: Humain WB, IF, IHC (p), ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2854801
  • Antigène Voir toutes MTDH Anticorps
    MTDH (Metadherin (MTDH))
    Reactivité
    • 49
    • 18
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 40
    • 7
    • 3
    Lapin
    Clonalité
    • 45
    • 5
    Polyclonal
    Conjugué
    • 28
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MTDH est non-conjugé
    Application
    • 40
    • 15
    • 13
    • 13
    • 11
    • 10
    • 8
    • 8
    • 6
    • 4
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Rabbit polyclonal antibody to LYRIC (metadherin)
    LYRIC antibody [N2C3]
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Recombinant protein encompassing a sequence within the center region of human LYRIC . The exact sequence is proprietary.
    Isotype
    IgG
  • Indications d'application
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Commentaires

    Positive Control: rat brain

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.69 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Agent conservateur
    Thimerosal (Merthiolate)
    Précaution d'utilisation
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Lai, Chuang, Liu, Ho, Lin, Anderson, Yeh: "Antibodies Against Modified NS1 Wing Domain Peptide Protect Against Dengue Virus Infection." dans: Scientific reports, Vol. 7, Issue 1, pp. 6975, (2019) (PubMed).

  • Antigène
    MTDH (Metadherin (MTDH))
    Autre désignation
    metadherin (MTDH Produits)
    Synonymes
    anticorps MGC75963, anticorps 2610103J23Rik, anticorps 3D3, anticorps 3D3/Lyric, anticorps AEG-1, anticorps AV353288, anticorps D8Bwg1112e, anticorps Lyric, anticorps AEG1, anticorps LYRIC, anticorps LYRIC/3D3, anticorps metadherin, anticorps mtdh, anticorps MTDH, anticorps Mtdh
    Sujet
    Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance.

    Cellular Localization: Endoplasmic reticulum membrane, Single-pass membrane protein , Nucleus membrane, Single-pass membrane protein (By similarity) , Cell junction , tight junction (By similarity) , Nucleus , nucleolus (By similarity) , Cytoplasm , perinuclear region
    Poids moléculaire
    64 kDa
    ID gène
    92140
    UniProt
    Q86UE4
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization
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