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MMP13 anticorps

MMP13 Reactivité: Humain WB, IHC, IF, ICC, IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2854829
  • Antigène Voir toutes MMP13 Anticorps
    MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))
    Reactivité
    • 113
    • 51
    • 36
    • 18
    • 10
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 120
    • 13
    • 7
    Lapin
    Clonalité
    • 122
    • 18
    Polyclonal
    Conjugué
    • 59
    • 20
    • 13
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp MMP13 est non-conjugé
    Application
    • 113
    • 58
    • 46
    • 27
    • 26
    • 25
    • 20
    • 15
    • 15
    • 8
    • 8
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Rabbit Polyclonal antibody to MMP13 (matrix metallopeptidase 13 (collagenase 3))
    MMP13 antibody [N3C1], Internal
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human MMP13. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product MMP13 Anticorps primaire
  • Indications d'application
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Commentaires

    Positive Control: NT2D1

    Validation: Orthogonal

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Agent conservateur
    Thimerosal (Merthiolate)
    Précaution d'utilisation
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Nakagawa, Lebaschi, Wada, Green, Wang, Album, Carballo, Deng, Rodeo: "Duration of postoperative immobilization affects MMP activity at the healing graft-bone interface: Evaluation in a mouse ACL reconstruction model." dans: Journal of orthopaedic research : official publication of the Orthopaedic Research Society, Vol. 37, Issue 2, pp. 325-334, (2019) (PubMed).

  • Antigène
    MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))
    Autre désignation
    matrix metallopeptidase 13 (MMP13 Produits)
    Synonymes
    anticorps CLG3, anticorps MANDP1, anticorps Clg, anticorps MMP-13, anticorps Mmp1, anticorps cb1034, anticorps mmp13, anticorps gene A, anticorps xCol, anticorps xcl3, anticorps MMP13, anticorps MGC108008, anticorps matrix metallopeptidase 13, anticorps matrix metallopeptidase 13a, anticorps matrix metallopeptidase 13 (collagenase 3) like S homeolog, anticorps matrix metallopeptidase 13 (collagenase 3), anticorps matrix metalloproteinase 13, anticorps matrix metallopeptidase 13 (collagenase 3) like L homeolog, anticorps MMP13, anticorps Mmp13, anticorps mmp13a, anticorps mmp13l.S, anticorps mmp13, anticorps LOC100136348, anticorps mmp13l.L
    Sujet
    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

    Cellular Localization: Secreted , extracellular space , extracellular matrix
    Poids moléculaire
    54 kDa
    ID gène
    4322
    UniProt
    P45452
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