RAC1 anticorps (Center)
-
- Antigène Voir toutes RAC1 Anticorps
- RAC1
-
Épitope
- Center
-
Reactivité
- Humain, Souris
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp RAC1 est non-conjugé
-
Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Réactivité croisée
- Poulet, Chien, Porc, Rat (Rattus), Xenopus laevis, Boeuf (Vache), Xenopus tropicalis
- Réactivité croisée (Details)
- Chicken (90 %), Dog (90 %), Pig (90 %), Rat (90 %), Xenopus laevis (90 %), Bovine (90 %), Xenopus tropicalis (90 %)
- Attributs du produit
-
Rabbit Polyclonal antibody to RAC1 (ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1))
RAC1 antibody - Purification
- Purified by antigen-affinity chromatography.
- Immunogène
- Recombinant protein encompassing a sequence within the center region of human RAC1. The exact sequence is proprietary.
- Isotype
- IgG
-
-
- Indications d'application
- Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
- Commentaires
-
Positive Control: 293T , A431 , HeLa , HepG2 , Molt-4 , Raji , mouse liver
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- Agent conservateur
- Thimerosal (Merthiolate)
- Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
Astrocytic CCAAT/Enhancer-Binding Protein Delta Contributes to Glial Scar Formation and Impairs Functional Recovery After Spinal Cord Injury." dans: Molecular neurobiology, Vol. 53, Issue 9, pp. 5912-5927, (2018) (PubMed).
: "Targeting of Rac GTPases blocks the spread of intact human breast cancer." dans: Oncotarget, Vol. 3, Issue 6, pp. 608-19, (2012) (PubMed).
: "
-
Astrocytic CCAAT/Enhancer-Binding Protein Delta Contributes to Glial Scar Formation and Impairs Functional Recovery After Spinal Cord Injury." dans: Molecular neurobiology, Vol. 53, Issue 9, pp. 5912-5927, (2018) (PubMed).
-
- Antigène
- RAC1
- Abstract
- RAC1 Produits
- Sujet
-
The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene.
Cellular Localization: Cell membrane, Lipid-anchor, Cytoplasmic side (By similarity) , Melanosome - Poids moléculaire
- 21 kDa
- ID gène
- 5879
- Pathways
- Signalisation WNT, Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Thromboxane A2 Receptor Signaling, VEGF Signaling
-