RAC1 anticorps (Center)

N° du produit ABIN2854858

Détail du produit anti-RAC1 anticorps

Antigène: RAC1

Épitope: Center

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAC1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Poulet, Chien, Porc, Rat (Rattus), Xenopus laevis, Boeuf (Vache), Xenopus tropicalis

Réactivité croisée (Details): Chicken (90 %), Dog (90 %), Pig (90 %), Rat (90 %), Xenopus laevis (90 %), Bovine (90 %), Xenopus tropicalis (90 %)

Attributs du produit: Rabbit Polyclonal antibody to RAC1 (ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1))
RAC1 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human RAC1. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Commentaires:

Positive Control: 293T , A431 , HeLa , HepG2 , Molt-4 , Raji , mouse liver

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-RAC1 (ABIN2854858)

Wang, Hsu, Ko, Chiu, Kan, Lai, Wang: "Astrocytic CCAAT/Enhancer-Binding Protein Delta Contributes to Glial Scar Formation and Impairs Functional Recovery After Spinal Cord Injury." dans: Molecular neurobiology, Vol. 53, Issue 9, pp. 5912-5927, (2018) (PubMed).

Katz, Sims, Sproul, Caldwell, Dixon, Meehan, Harrison: "Targeting of Rac GTPases blocks the spread of intact human breast cancer." dans: Oncotarget, Vol. 3, Issue 6, pp. 608-19, (2012) (PubMed).

Détails sur RAC1

Antigène: RAC1

Abstract: RAC1 Produits

Sujet: The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene.

Cellular Localization: Cell membrane, Lipid-anchor, Cytoplasmic side (By similarity) , Melanosome

Poids moléculaire: 21 kDa

ID gène: 5879

Pathways: Signalisation WNT, Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Thromboxane A2 Receptor Signaling, VEGF Signaling