Granulin anticorps (Center)

N° du produit ABIN2854868

Détail du produit anti-Granulin anticorps

Antigène: Granulin (GRN)

Épitope: Center

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Granulin est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Attributs du produit: Rabbit Polyclonal antibody to Granulins (granulin)
Granulins antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human Granulins. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Commentaires:

Positive Control: HepG2 , mouse kidney , rat kidney

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.48 mg/mL

Buffer: 1XPBS, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur Granulin

Antigène: Granulin (GRN)

Autre désignation: Granulins (GRN Produits)

Synonymes: anticorps GRN, anticorps grn, anticorps wu:fb11g12, anticorps wu:fj18f05, anticorps MGC53354, anticorps DKFZp459H066, anticorps CLN11, anticorps GEP, anticorps GP88, anticorps PCDGF, anticorps PEPI, anticorps PGRN, anticorps epithelin, anticorps acrogranin, anticorps granulin precursor, anticorps granulin a, anticorps Granulins, anticorps granulin L homeolog, anticorps granulin, anticorps GRN, anticorps grna, anticorps grn, anticorps grn.L, anticorps granulin, anticorps ORF1 granulin, anticorps Grn

Classe de substances: Viral Protein

Sujet: Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis.

Cellular Localization: Secreted

Poids moléculaire: 64 kDa

ID gène: 2896