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ube3a anticorps

ube3a Reactivité: Humain IF, IHC (p), ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2854930
  • Antigène Voir toutes ube3a Anticorps
    ube3a (Ubiquitin Protein Ligase E3A (ube3a))
    Reactivité
    • 51
    • 12
    • 8
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 46
    • 5
    Lapin
    Clonalité
    • 46
    • 5
    Polyclonal
    Conjugué
    • 28
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ube3a est non-conjugé
    Application
    • 28
    • 17
    • 16
    • 13
    • 13
    • 8
    • 8
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Rabbit Polyclonal antibody to UBE3A (ubiquitin protein ligase E3A)
    UBE3A antibody
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Recombinant protein encompassing a sequence within the center region of human UBE3A. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product ube3a Anticorps primaire
  • Indications d'application
    ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.26 mg/mL
    Buffer
    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    ube3a (Ubiquitin Protein Ligase E3A (ube3a))
    Autre désignation
    ubiquitin protein ligase E3A (ube3a Produits)
    Synonymes
    anticorps ANCR, anticorps AS, anticorps E6-AP, anticorps EPVE6AP, anticorps HPVE6A, anticorps DDBDRAFT_0188760, anticorps DDBDRAFT_0302447, anticorps DDB_0188760, anticorps DDB_0302447, anticorps ube3a, anticorps im:7140733, anticorps zgc:92173, anticorps 4732496B02, anticorps 5830462N02Rik, anticorps A130086L21Rik, anticorps Hpve6a, anticorps mKIAA4216, anticorps As, anticorps CG6190, anticorps Dmel\\CG6190, anticorps Dube3a, anticorps UBE3A, anticorps dUBE3A, anticorps das, anticorps dube3A, anticorps dube3a, anticorps MGC69536, anticorps UME3A, anticorps ubiquitin protein ligase E3A, anticorps ubiquitin-protein ligase E3A, anticorps Ubiquitin protein ligase E3A, anticorps ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome) S homeolog, anticorps ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome), anticorps UBE3A, anticorps ube3a, anticorps LOC100194730, anticorps Ube3a, anticorps ube3a.S, anticorps Eint_040430
    Sujet
    This gene encodes an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. This imprinted gene is maternally expressed in brain and biallelically expressed in other tissues. Maternally inherited deletion of this gene causes Angelman Syndrome, characterized by severe motor and intellectual retardation, ataxia, hypotonia, epilepsy, absence of speech, and characteristic facies. The protein also interacts with the E6 protein of human papillomavirus types 16 and 18, resulting in ubiquitination and proteolysis of tumor protein p53. Alternative splicing of this gene results in three transcript variants encoding three isoforms with different N-termini. Additional transcript variants have been described, but their full length nature has not been determined.

    Cellular Localization: Nucleus
    Poids moléculaire
    100 kDa
    ID gène
    7337
    UniProt
    Q05086
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway
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