Insulin Receptor anticorps (C-Term)
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- Antigène Voir toutes Insulin Receptor (INSR) Anticorps
- Insulin Receptor (INSR)
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Insulin Receptor est non-conjugé
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Application
- Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Réactivité croisée
- Humain, Souris, Rat, Poisson zèbre (Danio rerio)
- Attributs du produit
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Rabbit Polyclonal antibody to Insulin Receptor (insulin receptor)
Insulin Receptor antibody - Purification
- Purified by antigen-affinity chromatography.
- Classe de qualité
- KO Validated
- Immunogène
- Recombinant protein encompassing a sequence within the C-terminus region of human Insulin Receptor. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product INSR Anticorps primaire
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- Indications d'application
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Commentaires
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Positive Control: NIH-3T3 , PC-12 , rat liver
Validation: KO/KD
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.31 mg/mL
- Buffer
- 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Antigène
- Insulin Receptor (INSR)
- Autre désignation
- insulin receptor (INSR Produits)
- Sujet
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After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Two transcript variants encoding different isoforms have been found for this gene.
Cellular Localization: Membrane, Single-pass type I membrane protein - Poids moléculaire
- 156 kDa
- ID gène
- 3643
- UniProt
- P06213
- Pathways
- Signalisation NF-kappaB, Signalisation RTK, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
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