EIF2A anticorps (Center)

N° du produit ABIN2854984

Détail du produit anti-EIF2A anticorps

Antigène: EIF2A (Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A))

Épitope: Center

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF2A est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Réactivité croisée: Macaque rhésus

Réactivité croisée (Details): Rhesus Monkey (100 %)

Attributs du produit: Rabbit Polyclonal antibody to eIF2 alpha (eukaryotic translation initiation factor 2, subunit 1 alpha, 35 kDa)
eIF2 alpha antibody [N1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human eIF2 alpha. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*

Commentaires:

Positive Control: H1299 , Raji , *rat neuron , *HeLa , *N2a ,

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.31 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-EIF2A (ABIN2854984)

Wu, Yen, Kou, Wu: "Luteolin and Apigenin Attenuate 4-Hydroxy-2-Nonenal-Mediated Cell Death through Modulation of UPR, Nrf2-ARE and MAPK Pathways in PC12 Cells." dans: PLoS ONE, Vol. 10, Issue 6, pp. e0130599, (2016) (PubMed).

Détails sur EIF2A

Antigène: EIF2A (Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A))

Autre désignation: eIF2 alpha (EIF2A Produits)

Synonymes: anticorps ATEIF2-A2, anticorps EIF2-A2, anticorps eukaryotic translation initiation factor 2 alpha subunit, anticorps EIF-2A, anticorps MST089, anticorps MSTP004, anticorps MSTP089, anticorps D030048D22, anticorps D3Ertd194e, anticorps im:7145971, anticorps zgc:110460, anticorps DDBDRAFT_0185936, anticorps DDBDRAFT_0234177, anticorps DDB_0185936, anticorps DDB_0234177, anticorps Eif2a, anticorps eif2a, anticorps eif2alpha, anticorps EIF2A, anticorps CG9946, anticorps Dmel\\CG9946, anticorps Eif2alpha, anticorps IF2A_DROME, anticorps M(1)14C, anticorps M(1)19-153, anticorps M(1)8e3-10, anticorps deIF2alpha, anticorps eIF-2, anticorps eIF-2 a, anticorps eIF-2 alpha, anticorps eIF2 alpha, anticorps eIF2-alpha, anticorps eIF2a, anticorps eIF2alpha, anticorps eiF-2alpha, anticorps elF2alpha, anticorps l(1)14Cf, anticorps l(1)19-153, anticorps eukaryotic translation initiation factor 2 alpha subunit, anticorps eukaryotic translation initiation factor 2A, anticorps eukaryotic translation initiation factor 2A, 65kDa, anticorps eukaryotic translation initiation factor 2A S homeolog, anticorps eukaryotic translation initiation factor, anticorps eukaryotic translation Initiation Factor 2alpha, anticorps EIF2 ALPHA, anticorps EIF2A, anticorps Eif2a, anticorps eif2a, anticorps eIF2a, anticorps eif2a.S, anticorps eif2A, anticorps eIF-2alpha

Sujet: The translation initiation factor eIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, eIF2, and GTP. eIF2 is composed of 3 nonidentical subunits, alpha (36 kD), beta (38 kD, MIM 603908), and gamma (52 kD, MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of eIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM]

Poids moléculaire: 36 kDa

ID gène: 1965

Pathways: Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C, Methionine Biosynthetic Process, Ribosome Assembly