GBA anticorps (C-Term)

N° du produit ABIN2854995

Détail du produit anti-GBA anticorps

Antigène: GBA (Glucosidase, Beta, Acid (GBA))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GBA est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Réactivité croisée: Chimpanzé

Réactivité croisée (Details): Chimpanzee (100 %)

Attributs du produit: Rabbit Polyclonal antibody to GBA (glucosidase, beta, acid)
GBA antibody [C1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the C-terminus region of human GBA. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Commentaires:

Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.82 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur GBA

Antigène: GBA (Glucosidase, Beta, Acid (GBA))

Autre désignation: GBA (GBA Produits)

Synonymes: anticorps GBA1, anticorps GCB, anticorps GLUC, anticorps BETA-GLUCOSIDASE, anticorps T12J13.8, anticorps T12J13_8, anticorps beta glucosidase 25, anticorps PSPTO3318, anticorps PSPTO4290, anticorps GC, anticorps GCase, anticorps betaGC, anticorps glucosylceramidase beta, anticorps beta glucosidase 25, anticorps beta-glucosidase, anticorps Beta-glucosidase, anticorps glucosidase, beta, acid, anticorps glucosylceramidase, anticorps bglX-2, anticorps GBA, anticorps BGLU25, anticorps PSPTO_3318, anticorps bglX, anticorps bglA4, anticorps Gba, anticorps LOC100399524, anticorps bglA.2, anticorps bglX-2

Sujet: This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants encoding the same protein.

Cellular Localization: Lysosome membrane, Peripheral membrane protein, Lumenal side

Poids moléculaire: 60 kDa

ID gène: 2629

Pathways: Cellular Glucan Metabolic Process