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ATRX anticorps (C-Term)

ATRX Reactivité: Humain, Souris WB, IF, IHC (p), ICC, IP Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2855005
  • Antigène Voir toutes ATRX Anticorps
    ATRX (helicase 2, X-linked (ATRX))
    Épitope
    • 12
    • 6
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 57
    • 15
    • 3
    • 3
    • 2
    • 2
    Humain, Souris
    Hôte
    • 38
    • 21
    • 1
    Lapin
    Clonalité
    • 35
    • 25
    Polyclonal
    Conjugué
    • 35
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ATRX est non-conjugé
    Application
    • 34
    • 27
    • 19
    • 16
    • 15
    • 11
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunoprecipitation (IP)
     Réactivité croisée
    Chimpanzé
    Réactivité croisée (Details)
    Chimpanzee (100 %)
    Attributs du produit
    Rabbit Polyclonal antibody to ATRX (alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae))
    ATRX antibody [C3], C-term
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Recombinant protein encompassing a sequence within the C-terminus region of human ATRX. The exact sequence is proprietary.
    Isotype
    IgG
  • Indications d'application
    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Immunoprecipitation 1:100-1:500* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Immunoprecipitation1:100-1:500* Western blot1:500-1:3000*
    Commentaires

    Positive Control: 293T , A431 , HeLa , HepG2 , NIH3T3

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    2.67 mg/mL
    Buffer
    1XPBS, 20 % Glycerol ( pH 7). 0.025 % ProClin 300 was added as a preservative.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    ATRX (helicase 2, X-linked (ATRX))
    Autre désignation
    ATRX (ATRX Produits)
    Synonymes
    anticorps ATR2, anticorps JMS, anticorps MRXHF1, anticorps RAD54, anticorps RAD54L, anticorps SFM1, anticorps SHS, anticorps XH2, anticorps XNP, anticorps ZNF-HX, anticorps 4833408C14Rik, anticorps AI447451, anticorps DXHXS6677E, anticorps HP1-BP38, anticorps Hp1bp2, anticorps Hp1bp38, anticorps MRXS3, anticorps Rad54, anticorps Xnp, anticorps atrx, anticorps rad54, anticorps atrxl, anticorps wu:fb26e12, anticorps wu:fb52h08, anticorps wu:fb72g09, anticorps wu:fb94e07, anticorps zgc:66223, anticorps ATRX, chromatin remodeler, anticorps alpha thalassemia/mental retardation syndrome X-linked L homeolog, anticorps alpha thalassemia/mental retardation syndrome X-linked homolog (human), anticorps ATRX, anticorps Atrx, anticorps atrx.L, anticorps atrx
    Sujet
    The protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. The mutations of this gene are associated with an X-linked mental retardation (XLMR) syndrome most often accompanied by alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.

    Poids moléculaire
    283 kDa
    ID gène
    546
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