CCR5 anticorps (Center)
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- Antigène Voir toutes CCR5 Anticorps
- CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
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Épitope
- Center
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CCR5 est non-conjugé
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Application
- Western Blotting (WB)
- Attributs du produit
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Rabbit Polyclonal antibody to CCR5 (chemokine (C-C motif) receptor 5 (gene/pseudogene))
CCR5 antibody - Purification
- Purified by antigen-affinity chromatography.
- Immunogène
- Recombinant protein encompassing a sequence within the center region of human CCR5. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product CCR5 Anticorps primaire
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- Indications d'application
- Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
- Commentaires
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Positive Control: U87-MG , SK-N-SH , IMR32 , Jurkat , Raji , NCI-H929
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- 1XPBS, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- Agent conservateur
- Thimerosal (Merthiolate)
- Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Antigène
- CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
- Autre désignation
- CCR5 (CCR5 Produits)
- Synonymes
- anticorps CC-CKR-5, anticorps CCCKR5, anticorps CCR-5, anticorps CD195, anticorps CKR-5, anticorps CKR5, anticorps CMKBR5, anticorps IDDM22, anticorps Ckr5, anticorps Cmkbr5, anticorps CCR1-L, anticorps GPCR, anticorps CCR5, anticorps AM4-7, anticorps C-C motif chemokine receptor 5 (gene/pseudogene), anticorps chemokine (C-C motif) receptor 5, anticorps C-C motif chemokine receptor 5, anticorps CCR5, anticorps Ccr5
- Sujet
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This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene.
Cellular Localization: Cell membrane - Poids moléculaire
- 41 kDa
- ID gène
- 1234
- Pathways
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size
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