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PABPN1 anticorps

PABPN1 Reactivité: Humain WB, IF, ICC, IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2855064
  • Antigène Voir toutes PABPN1 Anticorps
    PABPN1 (Poly A Binding Protein Nuclear 1 (PABPN1))
    Reactivité
    • 39
    • 20
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    Humain
    Hôte
    • 39
    Lapin
    Clonalité
    • 30
    • 9
    Polyclonal
    Conjugué
    • 15
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp PABPN1 est non-conjugé
    Application
    • 24
    • 13
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Humain, Souris
    Attributs du produit
    Rabbit Polyclonal antibody to PABPN1 (poly(A) binding protein, nuclear 1)
    PABPN1 antibody
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Recombinant protein encompassing a sequence within the center region of human PABPN1. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product PABPN1 Anticorps primaire
  • Indications d'application
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Commentaires

    Positive Control: Mouse brain , Jurkat

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.49 mg/mL
    Buffer
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
    Agent conservateur
    Thimerosal (Merthiolate)
    Précaution d'utilisation
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    PABPN1 (Poly A Binding Protein Nuclear 1 (PABPN1))
    Autre désignation
    poly(A) binding protein nuclear 1 (PABPN1 Produits)
    Synonymes
    anticorps OPMD, anticorps PAB2, anticorps PABII, anticorps PABP-2, anticorps PABP2, anticorps Pabp3, anticorps mPABII, anticorps ARABIDOPSIS POLY(A) BINDING 2, anticorps ATPAB2, anticorps F28A23.130, anticorps F28A23_130, anticorps POLY(A) BINDING PROTEIN 2, anticorps POLY(A)-BINDING PROTEIN 2, anticorps poly(A) binding protein 2, anticorps opmd, anticorps pab2, anticorps pabp2, anticorps pabpii, anticorps pabpn1, anticorps Pabpn1, anticorps Poly(A)-binding protein 2, anticorps fb19c03, anticorps wu:fb17e03, anticorps wu:fb18c06, anticorps wu:fb19c03, anticorps zgc:85979, anticorps zgc:92452, anticorps poly(A) binding protein nuclear 1, anticorps poly(A) binding protein, nuclear 1, anticorps poly(A) binding protein 2, anticorps poly(A) binding protein, nuclear 1 S homeolog, anticorps poly(A) binding protein, nuclear 1 L homeolog, anticorps polyadenylate-binding protein 2, anticorps poly(A) binding protein Pab2, anticorps PABPN1, anticorps Pabpn1, anticorps PAB2, anticorps pabpn1.S, anticorps pabpn1.L, anticorps LOC100728725, anticorps pab2, anticorps pabpn1
    Sujet
    This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails on the 3' ends of eukaryotic genes and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. An expansion of the trinucleotide (GCG) repeat from normal 6 to 8-13 at the 5' end of the coding region of this gene leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Multiple splice variants have been described but their full-length nature is not known. One splice variant includes introns 1 and 6 but no protein is formed.

    Cellular Localization: Nucleus (By similarity) , Cytoplasm (By similarity)
    Poids moléculaire
    33 kDa
    ID gène
    8106
    UniProt
    Q86U42
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