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Calnexin anticorps (Internal Region)

CANX Reactivité: Humain, Souris, Rat WB, IF, ICC, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2855124
  • Antigène Voir toutes Calnexin (CANX) Anticorps
    Calnexin (CANX)
    Épitope
    • 49
    • 17
    • 13
    • 6
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 122
    • 79
    • 78
    • 49
    • 34
    • 31
    • 31
    • 29
    • 29
    • 26
    • 25
    • 25
    • 22
    • 21
    • 20
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 120
    • 25
    • 7
    Lapin
    Clonalité
    • 120
    • 33
    Polyclonal
    Conjugué
    • 70
    • 8
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Calnexin est non-conjugé
    Application
    • 122
    • 79
    • 58
    • 55
    • 40
    • 29
    • 26
    • 26
    • 21
    • 14
    • 13
    • 9
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Poulet, Chien, Xenopus laevis, Poisson zèbre (Danio rerio), Boeuf (Vache)
    Réactivité croisée (Details)
    Chicken (91 %), Dog (94 %), Xenopus laevis (88 %), Zebrafish (82 %), Bovine (94 %)
    Attributs du produit
    Rabbit Polyclonal antibody to Calnexin (calnexin)
    Calnexin antibody [N3C2], Internal
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Recombinant protein encompassing a sequence within the center region of human Calnexin. The exact sequence is proprietary.
    Isotype
    IgG
  • Indications d'application
    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:10000*
    Commentaires

    Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji , NIH-3T3 , PC-12 , Rat2

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.87 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Agent conservateur
    Thimerosal (Merthiolate)
    Précaution d'utilisation
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • de Jong, Murphy, Mäger, Willms, Garcia-Guerra, Gitz-Francois, Lefferts, Gupta, Steenbeek, van Rheenen, El Andaloussi, Schiffelers, Wood, Vader: "A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA." dans: Nature communications, Vol. 11, Issue 1, pp. 1113, (2020) (PubMed).

    Ilahibaks, Lei, Mol, Deshantri, Jiang, Schiffelers, Vader, Sluijter: "Biofabrication of Cell-Derived Nanovesicles: A Potential Alternative to Extracellular Vesicles for Regenerative Medicine." dans: Cells, Vol. 8, Issue 12, (2020) (PubMed).

    Sever, Vo, Bols, Dixon: "Rainbow trout (Oncorhynchus mykiss) contain two calnexin genes which encode distinct proteins." dans: Developmental and comparative immunology, Vol. 42, Issue 2, pp. 211-9, (2014) (PubMed).

  • Antigène
    Calnexin (CANX)
    Autre désignation
    Calnexin (CANX Produits)
    Synonymes
    anticorps CNX, anticorps IP90, anticorps P90, anticorps 1110069N15Rik, anticorps AI988026, anticorps Cnx, anticorps D11Ertd153e, anticorps canx, anticorps clgn, anticorps clnx, anticorps cnx, anticorps PP90, anticorps zgc:63524, anticorps wu:fe06b12, anticorps CANX, anticorps calnexin, anticorps CalNeXin, anticorps calnexin L homeolog, anticorps CANX, anticorps Canx, anticorps cnx-1, anticorps canx.L, anticorps canx, anticorps LOC100283947
    Sujet
    This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described.

    Cellular Localization: Endoplasmic reticulum membrane , Melanosome
    Poids moléculaire
    68 kDa
    ID gène
    821
    Pathways
    Signalisation MAPK, Thyroid Hormone Synthesis
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