XRCC6 anticorps (C-Term)
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- Antigène Voir toutes XRCC6 Anticorps
- XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp XRCC6 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunocytochemistry (ICC), Proximity Ligation Assay (PLA)
- Réactivité croisée
- Humain, Souris
- Attributs du produit
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Rabbit Polyclonal antibody to Ku70 (X-ray repair complementing defective repair in Chinese hamster cells 6)
Ku70 antibody - Purification
- Purified by antigen-affinity chromatography.
- Immunogène
- Recombinant protein encompassing a sequence within the C-terminus region of human Ku70. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product XRCC6 Anticorps primaire
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- Indications d'application
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:500-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Commentaires
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Positive Control: 293T , A431 , HeLa , HepG2
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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Classical non-homologous end-joining pathway utilizes nascent RNA for error-free double-strand break repair of transcribed genes." dans: Nature communications, Vol. 7, pp. 13049, (2018) (PubMed).
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Classical non-homologous end-joining pathway utilizes nascent RNA for error-free double-strand break repair of transcribed genes." dans: Nature communications, Vol. 7, pp. 13049, (2018) (PubMed).
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- Antigène
- XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))
- Autre désignation
- X-ray repair cross complementing 6 (XRCC6 Produits)
- Synonymes
- anticorps CTC75, anticorps CTCBF, anticorps G22P1, anticorps KU70, anticorps ML8, anticorps TLAA, anticorps 70kDa, anticorps G22p1, anticorps Ku70, anticorps Kup70, anticorps X-ray repair cross complementing 6, anticorps ATP-dependent DNA helicase II, 70 kDa subunit, anticorps X-ray repair complementing defective repair in Chinese hamster cells 6 L homeolog, anticorps X-ray repair complementing defective repair in Chinese hamster cells 6, anticorps XRCC6, anticorps Bm1_41430, anticorps xrcc6.L, anticorps Xrcc6
- Sujet
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The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
Cellular Localization: Nucleus - Poids moléculaire
- 70 kDa
- ID gène
- 2547
- UniProt
- P12956
- Pathways
- Réparation de l'ADN
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