PUF60 anticorps

N° du produit ABIN2855270

Détail du produit anti-PUF60 anticorps

Antigène: PUF60 (Poly-U Binding Splicing Factor 60KDa (PUF60))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PUF60 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Réactivité croisée: Humain

Attributs du produit: Rabbit Polyclonal antibody to PUF60 (poly-U binding splicing factor 60KDa)
PUF60 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human PUF60. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: A431

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.75 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur PUF60

Antigène: PUF60 (Poly-U Binding Splicing Factor 60KDa (PUF60))

Autre désignation: poly(U) binding splicing factor 60 (PUF60 Produits)

Synonymes: anticorps FIR, anticorps RoBPI, anticorps SIAHBP1, anticorps fc21a05, anticorps wu:fc21a05, anticorps wu:fi43a08, anticorps 2410104I19Rik, anticorps 2810454F19Rik, anticorps Siahbp1, anticorps fe37c05, anticorps repressor, anticorps si:ch211-12p8.2, anticorps si:zc12p8.2, anticorps wu:fb33e11, anticorps wu:fe37c05, anticorps zgc:86806, anticorps poly(U) binding splicing factor 60, anticorps poly-U binding splicing factor a, anticorps poly-U binding splicing factor 60, anticorps poly-U binding splicing factor b, anticorps PUF60, anticorps puf60a, anticorps Puf60, anticorps puf60b

Sujet: The protein encoded by this gene is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene.

Cellular Localization: Nucleus

Poids moléculaire: 60 kDa

ID gène: 22827

UniProt: Q9UHX1