ING3 anticorps

N° du produit ABIN2855406

Détail du produit anti-ING3 anticorps

Antigène: ING3 (Inhibitor of Growth Family, Member 3 (ING3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ING3 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Humain

Attributs du produit: Rabbit polyclonal antibody to ING3 (inhibitor of growth family, member 3)
ING3 antibody [N2N3]

Purification: Purified by antigen-affinity chromatography.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human ING3. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: H1299

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 40 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur ING3

Antigène: ING3 (Inhibitor of Growth Family, Member 3 (ING3))

Autre désignation: inhibitor of growth family member 3 (ING3 Produits)

Synonymes: anticorps ING3, anticorps Eaf4, anticorps ING2, anticorps MEAF4, anticorps p47ING3, anticorps 1300013A07Rik, anticorps P47ING3, anticorps zgc:56327, anticorps inhibitor of growth family member 3, anticorps inhibitor of growth family, member 3, anticorps inhibitor of growth protein 3, anticorps inhibitor of growth family member 3 L homeolog, anticorps ING3, anticorps Ing3, anticorps CpipJ_CPIJ009396, anticorps ing3, anticorps ing3.L

Sujet: The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed.

Cellular Localization: Nucleus

Poids moléculaire: 47 kDa

ID gène: 54556

UniProt: Q9NXR8