PIGA anticorps

N° du produit ABIN2855435

Détail du produit anti-PIGA anticorps

Antigène: PIGA (Phosphatidylinositol Glycan Anchor Biosynthesis, Class A (PIGA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIGA est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Souris

Attributs du produit: Rabbit Polyclonal antibody to PIGA (phosphatidylinositol glycan anchor biosynthesis, class A)
PIGA antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human PIGA. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: NIH-3T3

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.18 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 1 % BSA, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur PIGA

Antigène: PIGA (Phosphatidylinositol Glycan Anchor Biosynthesis, Class A (PIGA))

Autre désignation: phosphatidylinositol glycan anchor biosynthesis class A (PIGA Produits)

Synonymes: anticorps GPI3, anticorps MCAHS2, anticorps PIG-A, anticorps AI194334, anticorps Pig-a, anticorps im:6911675, anticorps zgc:56589, anticorps phosphatidylinositol glycan anchor biosynthesis class A, anticorps phosphatidylinositol glycan anchor biosynthesis, class A, anticorps PIGA, anticorps Piga, anticorps piga

Sujet: This gene encodes a protein required for synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the biosynthetic pathway of GPI anchor. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. Paroxysmal nocturnal hemoglobinuria, an acquired hematologic disorder, has been shown to result from mutations in this gene. Alternate splice variants have been characterized.

Cellular Localization: Endoplasmic reticulum membrane, Single-pass membrane protein

Poids moléculaire: 54 kDa

ID gène: 5277

UniProt: P37287

Pathways: Inositol Metabolic Process