CDC42BPA anticorps
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- Antigène Voir toutes CDC42BPA Anticorps
- CDC42BPA (CDC42 Binding Protein Kinase alpha (DMPK-Like) (CDC42BPA))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CDC42BPA est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Réactivité croisée
- Humain
- Attributs du produit
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Rabbit Polyclonal antibody to MRCK alpha (CDC42 binding protein kinase alpha (DMPK-like))
MRCK alpha antibody - Purification
- Affinity purified by Protein A.
- Immunogène
- Recombinant protein encompassing a sequence within the center region of human MRCK alpha. The exact sequence is proprietary.
- Isotype
- IgG
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- Indications d'application
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Commentaires
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Positive Control: U87-MG
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 2 mg/mL
- Buffer
- 1XPBS ( pH 7), 40 % Glycerol, 0.01 % Thimerosal
- Agent conservateur
- Thimerosal (Merthiolate)
- Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Antigène
- CDC42BPA (CDC42 Binding Protein Kinase alpha (DMPK-Like) (CDC42BPA))
- Autre désignation
- CDC42 binding protein kinase alpha (CDC42BPA Produits)
- Synonymes
- anticorps MRCK, anticorps MRCKA, anticorps PK428, anticorps Mrck, anticorps Pk428, anticorps A930014J19Rik, anticorps DMPK-like, anticorps CDC42BPA, anticorps CDC42 binding protein kinase alpha, anticorps GDNF family receptor alpha 2, anticorps serine/threonine-protein kinase MRCK alpha, anticorps CDC42 binding protein kinase alpha (DMPK-like), anticorps CDC42BPA, anticorps Cdc42bpa, anticorps GFRA2, anticorps LOC100182779, anticorps LOC100545977
- Sujet
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The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported.
Cellular Localization: Cytoplasm (By similarity) - Poids moléculaire
- 197 kDa
- ID gène
- 8476
- UniProt
- Q5VT25
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