NFE2 anticorps (Center)

N° du produit ABIN2855460

Détail du produit anti-NFE2 anticorps

Antigène: NFE2 (Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2))

Épitope: Center

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NFE2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), ChIP DNA-Sequencing (ChIP-seq)

Réactivité croisée: Singe, Porc

Réactivité croisée (Details): Monkey (97 %), Pig (91 %)

Attributs du produit: Rabbit Polyclonal antibody to NF-E2 (nuclear factor (erythroid-derived 2), 45 kDa)
NF-E2 antibody [N1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human NF-E2. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference ICC/IF 1:100-1:1000* Immunoprecipitation Assay-dependent dilution Western blot 1:500-1:3000* ChIP-sequencing Assay-dependent dilution Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* ImmunoprecipitationAssay-dependent dilution Western blot1:500-1:3000* ChIP-sequencingAssay-dependent dilution

Commentaires:

Positive Control: 293T , mouse spleen

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.03 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur NFE2

Antigène: NFE2 (Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2))

Autre désignation: NF-E2 (NFE2 Produits)

Synonymes: anticorps NF-E2, anticorps p45, anticorps 45kDa, anticorps p45NFE2, anticorps p45nf-e2, anticorps nuclear factor, erythroid 2, anticorps nuclear factor, erythroid derived 2, anticorps NFE2, anticorps Nfe2

Sujet: Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.

Cellular Localization: Nucleus

Poids moléculaire: 41 kDa

ID gène: 4778