HLA-DPB1 anticorps
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- Antigène Voir toutes HLA-DPB1 Anticorps
- HLA-DPB1 (Major Histocompatibility Complex, Class II, DP beta 1 (HLA-DPB1))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp HLA-DPB1 est non-conjugé
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Application
- Western Blotting (WB)
- Réactivité croisée
- Humain
- Attributs du produit
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Rabbit Polyclonal antibody to HLA-DPB1 (major histocompatibility complex, class II, DP beta 1)
HLA-DPB1 antibody - Purification
- Purified by antigen-affinity chromatography.
- Immunogène
- Recombinant protein encompassing a sequence within the center region of human HLA-DPB1. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product HLA-DPB1 Anticorps primaire
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- Indications d'application
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Commentaires
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Positive Control: Raji
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
- Agent conservateur
- Thimerosal (Merthiolate)
- Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Antigène
- HLA-DPB1 (Major Histocompatibility Complex, Class II, DP beta 1 (HLA-DPB1))
- Autre désignation
- major histocompatibility complex, class II, DP beta 1 (HLA-DPB1 Produits)
- Synonymes
- anticorps PATR-DPB1, anticorps B-LB, anticorps B-LB2, anticorps B-LB21, anticorps BLB1, anticorps GSP-BLB1, anticorps DPB1, anticorps HLA-DP, anticorps HLA-DP1B, anticorps HLA-DPB, anticorps major histocompatibility complex, class II, DP beta 1, anticorps Major histocompatibility complex class II beta chain BLB1, anticorps PATR-DPB1, anticorps BLB1, anticorps HLA-DPB1
- Sujet
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HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.
Cellular Localization: Membrane, Single-pass type I membrane protein - Poids moléculaire
- 29 kDa
- ID gène
- 3115
- UniProt
- P04440
- Pathways
- TCR Signaling, Cancer Immune Checkpoints, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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