Exportin 2 anticorps (Center)

N° du produit ABIN2855534

Détail du produit anti-Exportin 2 anticorps

Antigène: Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))

Épitope: Center

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Exportin 2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Réactivité croisée: Porc, Macaque rhésus, Boeuf (Vache)

Réactivité croisée (Details): Pig (100 %), Rhesus Monkey (100 %), Bovine (100 %)

Attributs du produit: Rabbit Polyclonal antibody to CSE1L (CSE1 chromosome segregation 1-like (yeast))
CSE1L antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human CSE1L. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Immunoprecipitation Assay-dependent dilution Western blot 1:500-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* ImmunoprecipitationAssay-dependent dilution Western blot1:500-1:10000*

Commentaires:

Positive Control: NIH-3T3 , JC , BCL-1 , C2C12 , 293T , A431 , HeLa , HepG2 , A375 , PC-12 , Rat2

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.71 mg/mL

Buffer: 1XPBS, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur Exportin 2

Antigène: Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))

Autre désignation: CSE1L (CSE1L Produits)

Synonymes: anticorps BcDNA:LD14270, anticorps CAS, anticorps CG13281, anticorps Dcas, anticorps Dmel\\CG13281, anticorps cas, anticorps dcas, anticorps l(2)k03902, anticorps CSE1L, anticorps XPO2, anticorps Exportin-2, anticorps DKFZp459E1929, anticorps 2610100P18Rik, anticorps AA407533, anticorps Capts, anticorps Cas, anticorps Xpo2, anticorps xpo2, anticorps CSE1, anticorps CAS/CSE1 segregation protein, anticorps chromosome segregation 1 like, anticorps exportin-2, anticorps chromosome segregation 1-like (S. cerevisiae), anticorps CSE1 chromosome segregation 1-like (yeast), anticorps CSE1 chromosome segregation 1-like L homeolog, anticorps Cas, anticorps CSE1L, anticorps LOC100542094, anticorps cse1l, anticorps Cse1l, anticorps cse1l.L

Sujet: Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation.

Cellular Localization: Cytoplasm , Nucleus

Poids moléculaire: 110 kDa

ID gène: 1434

Pathways: Protein targeting to Nucleus