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NRF1 anticorps

NRF1 Reactivité: Humain WB, IHC (p), IF, ICC, IP Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2855569
  • Antigène Voir toutes NRF1 Anticorps
    NRF1 (Nuclear Respiratory Factor 1 (NRF1))
    Reactivité
    • 71
    • 43
    • 36
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 68
    • 5
    Lapin
    Clonalité
    • 60
    • 13
    Polyclonal
    Conjugué
    • 36
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NRF1 est non-conjugé
    Application
    • 60
    • 29
    • 14
    • 14
    • 13
    • 11
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP)
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Rabbit Polyclonal antibody to NRF1 (nuclear respiratory factor 1)
    NRF1 antibody
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Recombinant protein encompassing a sequence within the center region of human NRF1. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product NRF1 Anticorps primaire
  • Indications d'application
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Commentaires

    Positive Control: 293T nuclear , A431 nuclear , HeLa nuclear , HepG2 nuclear

    Validation: Orthogonal

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.32 mg/mL
    Buffer
    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Mesquita, Lamb, Parry, Moore, Smith, Vann, Osburn, Fox, Ruple, Huggins, Fruge, Young, Kavazis, Roberts: "Acute and chronic effects of resistance training on skeletal muscle markers of mitochondrial remodeling in older adults." dans: Physiological reports, Vol. 8, Issue 15, pp. e14526, (2020) (PubMed).

    Ma, Cheng, Mu, Geng, Zhao, Luo, Ma, Chang, Liu, Gao, Nie, Xie, Han, Chen, Ma, Zhu, Chen: "The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression." dans: Nature communications, Vol. 10, Issue 1, pp. 1034, (2019) (PubMed).

  • Antigène
    NRF1 (Nuclear Respiratory Factor 1 (NRF1))
    Autre désignation
    nuclear respiratory factor 1 (NRF1 Produits)
    Synonymes
    anticorps ALPHA-PAL, anticorps C87038, anticorps D6Ertd415e, anticorps SC:BZ3C13.1, anticorps SC:bZ3C13.2, anticorps ube2h, anticorps Nfe2l1_retired, anticorps IBR/F, anticorps NRF1, anticorps alpha-pal, anticorps nrf-1, anticorps LOC100220087, anticorps nuclear respiratory factor 1, anticorps nuclear respiratory factor 1 S homeolog, anticorps NRF1, anticorps Nrf1, anticorps nrf1, anticorps nrf1.S
    Sujet
    This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternate transcriptional splice variants, which encode the same protein, have been characterized. Additional variants encoding different protein isoforms have been described but they have not been fully characterized. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2)-like 1" which has an official symbol of NFE2L1.

    Cellular Localization: Nucleus
    Poids moléculaire
    54 kDa
    ID gène
    4899
    UniProt
    Q16656
    Pathways
    Regulation of Lipid Metabolism by PPARalpha
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