RRM2 anticorps (Regulatory Subunit)

N° du produit ABIN2855573

Détail du produit anti-RRM2 anticorps

Antigène: RRM2 (Ribonucleotide Reductase M2 (RRM2))

Épitope: Regulatory Subunit

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RRM2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Réactivité croisée: Humain, Souris, Rat, Poisson zèbre (Danio rerio)

Attributs du produit: Rabbit Polyclonal antibody to RRM2 (ribonucleotide reductase M2)
RRM2 antibody [N1C1]

Purification: Purified by antigen-affinity chromatography.

Classe de qualité: KO Validated

Immunogène: Recombinant protein encompassing a sequence within the center region of human RRM2. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Validatio: KO/KD, Orthogonal

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.18 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-RRM2 (ABIN2855573)

Su, Wu, Ko, Tsai, Tee, Chien, Chou, Lin, Low, Chou, Yang, Wang: "The expression of ribonucleotide reductase M2 in the carcinogenesis of uterine cervix and its relationship with clinicopathological characteristics and prognosis of cancer patients." dans: PLoS ONE, Vol. 9, Issue 3, pp. e91644, (2015) (PubMed).

Détails sur RRM2

Antigène: RRM2 (Ribonucleotide Reductase M2 (RRM2))

Autre désignation: ribonucleotide reductase M2 (RRM2 Produits)

Sujet: This gene encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion.

Cellular Localization: Cytoplasm

Poids moléculaire: 45 kDa

ID gène: 6241

UniProt: P31350

Pathways: Mitotic G1-G1/S Phases