Kallikrein 7 anticorps

N° du produit ABIN2855653

Détail du produit anti-Kallikrein 7 anticorps

Antigène: Kallikrein 7 (KLK7)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Kallikrein 7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris

Attributs du produit: Rabbit Polyclonal antibody to KLK7 (kallikrein-related peptidase 7)
KLK7 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human Kallikrein 7. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:1000-1:10000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: Kallikrein 7-transfected 293T

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.69 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-Kallikrein 7 (ABIN2855653)

Delaunay, Deschamps, Haddada, Walker, Soosaipillai, Soualmia, El Amri, Diamandis, Brattsand, Magdolen, Darmoul: "Aberrant expression of kallikrein-related peptidase 7 is correlated with human melanoma aggressiveness by stimulating cell migration and invasion." dans: Molecular oncology, Vol. 11, Issue 10, pp. 1330-1347, (2018) (PubMed).

Détails sur Kallikrein 7

Antigène: Kallikrein 7 (KLK7)

Autre désignation: kallikrein related peptidase 7 (KLK7 Produits)

Synonymes: anticorps Prss6, anticorps SCCE, anticorps PRSS6, anticorps hK7, anticorps kallikrein related-peptidase 7 (chymotryptic, stratum corneum), anticorps kallikrein-related peptidase 7, anticorps kallikrein related peptidase 7, anticorps Klk7, anticorps KLK7

Sujet: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded enzyme is thought to be involved in the proteolysis of intercellular cohesive structures preceding desquamation, which is the shedding of the outermost layer of the epidermis. Alternative splicing of this gene results in two transcript variants encoding the same protein.

Cellular Localization: Secreted

Poids moléculaire: 28 kDa

ID gène: 5650

UniProt: P49862

Pathways: Système du Complément