AKR1C4 anticorps

N° du produit ABIN2855666

Détail du produit anti-AKR1C4 anticorps

Antigène: AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AKR1C4 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Réactivité croisée: Humain

Attributs du produit: Rabbit polyclonal antibody to HSD3a (aldo-keto reductase family 1, member C4 (chlordecone reductase, 3-alpha hydroxysteroid dehydrogenase, type I, dihydrodiol dehydrogenase 4))
HSD3a antibody [N1C2]

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human HSD3a. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: HeLa

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.83 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur AKR1C4

Antigène: AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))

Autre désignation: aldo-keto reductase family 1 member C4 (AKR1C4 Produits)

Synonymes: anticorps 3-alpha-HSD, anticorps C11, anticorps CDR, anticorps CHDR, anticorps DD-4, anticorps DD4, anticorps HAKRA, anticorps aldo-keto reductase family 1 member C4, anticorps AKR1C4

Sujet: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

Cellular Localization: Cytoplasm

Poids moléculaire: 37 kDa

ID gène: 1109

UniProt: P17516

Pathways: Steroid Hormone Biosynthesis