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FGFRL1 anticorps

FGFRL1 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2855700
  • Antigène Voir toutes FGFRL1 Anticorps
    FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))
    Reactivité
    • 51
    • 13
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 52
    • 1
    • 1
    Lapin
    Clonalité
    • 52
    • 2
    Polyclonal
    Conjugué
    • 19
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FGFRL1 est non-conjugé
    Application
    • 42
    • 22
    • 21
    • 13
    • 13
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain
    Attributs du produit
    Rabbit polyclonal antibody to FGFR-5 (fibroblast growth factor receptor-like 1)
    FGFR-5 antibody
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Recombinant protein encompassing a sequence within the center region of human FGFR5. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product FGFRL1 Anticorps primaire
  • Indications d'application
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Commentaires

    Positive Control: FGFRL1-transfected 293T , HepG2 membrane extract

    Validation: Orthogonal, Overexpression

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    2.42 mg/mL
    Buffer
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))
    Autre désignation
    fibroblast growth factor receptor like 1 (FGFRL1 Produits)
    Synonymes
    anticorps fgfrl1, anticorps zgc:64084, anticorps FGFR5, anticorps FGFR5beta, anticorps FGFR5gamma, anticorps Fgfr5, anticorps FHFR, anticorps XFGFRL1, anticorps Xndk, anticorps fgfrl1-a, anticorps fgfrl1-b, anticorps ndk, anticorps im:7154242, anticorps fibroblast growth factor receptor like 1a, anticorps fibroblast growth factor receptor-like 1, anticorps fibroblast growth factor receptor like 1, anticorps fibroblast growth factor receptor like 1 L homeolog, anticorps fibroblast growth factor receptor like 1b, anticorps fgfrl1a, anticorps Fgfrl1, anticorps FGFRL1, anticorps fgfrl1.L, anticorps fgfrl1b
    Sujet
    The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene.

    Cellular Localization: Membrane, Single-pass type I membrane protein
    Poids moléculaire
    55 kDa
    ID gène
    53834
    UniProt
    Q8N441
    Pathways
    Signalisation RTK
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