TPP1 anticorps

N° du produit ABIN2855723

Détail du produit anti-TPP1 anticorps

Antigène: TPP1 (Tripeptidyl Peptidase I (TPP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TPP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain

Attributs du produit: Rabbit Polyclonal antibody to TPP1 (tripeptidyl peptidase I)
TPP1 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human TPP1. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: A431

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur TPP1

Antigène: TPP1 (Tripeptidyl Peptidase I (TPP1))

Autre désignation: tripeptidyl peptidase 1 (TPP1 Produits)

Synonymes: anticorps cln2, anticorps fa01b09, anticorps im:7149243, anticorps wu:fa01b09, anticorps CLN2, anticorps LPIC, anticorps TPP-1, anticorps TPP-I, anticorps Cln2, anticorps tripeptidyl peptidase I, anticorps tripeptidyl-peptidase 1, anticorps tripeptidyl peptidase 1, anticorps tpp1, anticorps NAEGRDRAFT_78259, anticorps MCYG_00184, anticorps MGYG_05881, anticorps MGYG_00757, anticorps TPP1, anticorps Tpp1

Sujet: This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.

Cellular Localization: Lysosome , Melanosome

Poids moléculaire: 61 kDa

ID gène: 1200

UniProt: O14773

Pathways: Cycle Cellulaire, ER-Nucleus Signaling