CD55 anticorps (Center)

N° du produit ABIN2855732

Détail du produit anti-CD55 anticorps

Antigène: CD55 (Complement Decay-Accelerating Factor (CD55))

Épitope: Center

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD55 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Attributs du produit: Rabbit Polyclonal antibody to CD55 (CD55 Molecule, decay accelerating factor for complement (Cromer blood group))
CD55 antibody [N2C3]

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human CD55. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*

Commentaires:

Positive Control: K562 , THP-1

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-CD55 (ABIN2855732)

Kwon, Kim, Hwang, Kim, Kim, Kim, Lee, Im, Lee, Hwang: "Generation of α-1,3-galactosyltransferase knocked-out transgenic cloned pigs with knocked-in five human genes." dans: Transgenic research, Vol. 26, Issue 1, pp. 153-163, (2018) (PubMed).

Détails sur CD55

Antigène: CD55 (Complement Decay-Accelerating Factor (CD55))

Autre désignation: CD55 (CD55 Produits)

Synonymes: anticorps CR, anticorps CROM, anticorps DAF, anticorps TC, anticorps Daf, anticorps Daf-GPI, anticorps Daf1, anticorps GPI-DAF, anticorps CD55 molecule (Cromer blood group), anticorps CD55 molecule, decay accelerating factor for complement, anticorps CD55, anticorps Cd55

Sujet: This gene encodes a protein involved in the regulation of the complement cascade. The encoded glycoprotein is also known as the decay-accelerating factor (DAF), binding of DAF to complement proteins accelerates their decay, disrupting the cascade and preventing damage to host cells. Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM). Two alternatively spliced transcripts encoding different proteins have been identified. The predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels. Additional, alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Cellular Localization: Isoform 1: Membrane , Isoform 2: Cell membrane , GPI-anchor

Poids moléculaire: 41 kDa

ID gène: 1604

Pathways: Système du Complément, Regulation of Leukocyte Mediated Immunity