EIF4E2 anticorps

N° du produit ABIN2855740

Détail du produit anti-EIF4E2 anticorps

Antigène: EIF4E2 (Eukaryotic Translation Initiation Factor 4E Family Member 2 (EIF4E2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF4E2 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Réactivité croisée: Humain, Souris

Attributs du produit: Rabbit polyclonal antibody to EIF4EL3 (eukaryotic translation initiation factor 4E family member 2)
EIF4E2 antibody [N1C3]

Purification: Purified by antigen-affinity chromatography.

Classe de qualité: KO Validated

Immunogène: Recombinant protein encompassing a sequence within the center region of human EIF4E2. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Validation: KO/KD

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.27 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-EIF4E2 (ABIN2855740)

Juszkiewicz, Slodkowicz, Lin, Freire-Pritchett, Peak-Chew, Hegde: "Ribosome collisions trigger cis-acting feedback inhibition of translation initiation." dans: eLife, Vol. 9, (2020) (PubMed).

Garzia, Jafarnejad, Meyer, Chapat, Gogakos, Morozov, Amiri, Shapiro, Molina, Tuschl, Sonenberg: "The E3 ubiquitin ligase and RNA-binding protein ZNF598 orchestrates ribosome quality control of premature polyadenylated mRNAs." dans: Nature communications, Vol. 8, pp. 16056, (2018) (PubMed).

Détails sur EIF4E2

Antigène: EIF4E2 (Eukaryotic Translation Initiation Factor 4E Family Member 2 (EIF4E2))

Autre désignation: eukaryotic translation initiation factor 4E family member 2 (EIF4E2 Produits)

Synonymes: anticorps 4E-LP, anticorps 4EHP, anticorps EIF4EL3, anticorps IF4e, anticorps Eif4el3, anticorps EIF4E2, anticorps id:ibd1007, anticorps zgc:110542, anticorps zgc:158544, anticorps MGC115622, anticorps 2700069E09Rik, anticorps AI036339, anticorps AV129531, anticorps D0H0S6743E, anticorps eukaryotic translation initiation factor 4E family member 2, anticorps eukaryotic translation initiation factor 4E member 2, anticorps eukaryotic translation initiation factor 4E family member 2 L homeolog, anticorps EIF4E2, anticorps Eif4e2, anticorps eif4e2, anticorps eif4e2.L

Sujet: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.

Poids moléculaire: 28 kDa

ID gène: 9470

UniProt: O60573

Pathways: SARS-CoV-2 Protein Interactome