GOLGA5 anticorps

N° du produit ABIN2855796

Détail du produit anti-GOLGA5 anticorps

Antigène: GOLGA5 (Golgin A5 (GOLGA5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GOLGA5 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Réactivité croisée: Hamster, Humain, Souris

Attributs du produit: Rabbit Polyclonal antibody to GOLGA5 (golgin A5)
GOLGA5 antibody [N2C2], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human GOLGA5. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: Mouse brain , A549

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-GOLGA5 (ABIN2855796)

Pérez-Rodriguez, de Jesús Ramírez-Lira, Wulff, Voldbor, Ramírez, Trujillo-Roldán, Valdez-Cruz: "Enrichment of microsomes from Chinese hamster ovary cells by subcellular fractionation for its use in proteomic analysis." dans: PLoS ONE, Vol. 15, Issue 8, pp. e0237930, (2020) (PubMed).

Popa, Villeneuve, Stewart, Perez Garcia, Petrunkina Harrison, Moreau: "Genome-wide CRISPR screening identifies new regulators of glycoprotein secretion." dans: Wellcome open research, Vol. 4, pp. 119, (2019) (PubMed).

Chang, Chen, Shen, Kung, Chuang, Chen: "Selective serotonin reuptake inhibitor, fluoxetine, impairs E-cadherin-mediated cell adhesion and alters calcium homeostasis in pancreatic beta cells." dans: Scientific reports, Vol. 7, Issue 1, pp. 3515, (2019) (PubMed).

Reiling, Olive, Sanyal, Carette, Brummelkamp, Ploegh, Starnbach, Sabatini: "A CREB3-ARF4 signalling pathway mediates the response to Golgi stress and susceptibility to pathogens." dans: Nature cell biology, Vol. 15, Issue 12, pp. 1473-85, (2013) (PubMed).

Détails sur GOLGA5

Antigène: GOLGA5 (Golgin A5 (GOLGA5))

Autre désignation: golgin A5 (GOLGA5 Produits)

Synonymes: anticorps GOLIM5, anticorps RFG5, anticorps ret-II, anticorps golim5, anticorps ret-ii, anticorps rfg5, anticorps Ret-II, anticorps im:7153094, anticorps sb:cb898, anticorps wu:fd50h11, anticorps zgc:66400, anticorps golgin A5, anticorps golgin A5 L homeolog, anticorps golgi autoantigen, golgin subfamily a, 5, anticorps GOLGA5, anticorps golga5.L, anticorps golga5, anticorps Golga5

Sujet: The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes a member of the golgin family of proteins, whose members localize to the Golgi. This protein is a coiled-coil membrane protein that has been postulated to play a role in vesicle tethering and docking. Translocations involving this gene and the ret proto-oncogene have been found in tumor tissues, the chimeric sequences have been designated RET-II and PTC5.

Cellular Localization: Golgi apparatus membrane, Single-pass type IV membrane protein

Poids moléculaire: 83 kDa

ID gène: 9950

UniProt: Q8TBA6