PSMC6 anticorps

N° du produit ABIN2855808

Détail du produit anti-PSMC6 anticorps

Antigène: PSMC6 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 6 (PSMC6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMC6 est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris

Attributs du produit: Rabbit Polyclonal antibody to PSMC6 (proteasome (prosome, macropain) 26S subunit, ATPase, 6)
PSMC6 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human PSMC6. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: Mouse brain , 293T

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur PSMC6

Antigène: PSMC6 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 6 (PSMC6))

Autre désignation: proteasome 26S subunit, ATPase 6 (PSMC6 Produits)

Synonymes: anticorps DDBDRAFT_0186051, anticorps DDBDRAFT_0232968, anticorps DDB_0186051, anticorps DDB_0232968, anticorps fb20g04, anticorps wu:fb20g04, anticorps wu:fc85c10, anticorps cadp44, anticorps sug2, anticorps PSMC6, anticorps psmc6-a, anticorps NV13405, anticorps CADP44, anticorps P44, anticorps SUG2, anticorps p42, anticorps 2300001E01Rik, anticorps AI451058, anticorps 26S protease regulatory subunit S10B, anticorps 26S proteasome regulatory subunit 10B, anticorps proteasome 26S subunit, ATPase 6, anticorps proteasome 26S subunit, ATPase 6 L homeolog, anticorps 26S protease regulatory subunit 10B, anticorps proteasome 26S subunit, ATPase 6 S homeolog, anticorps proteasome (prosome, macropain) 26S subunit, ATPase, 6, anticorps ATEG_02903, anticorps HCAG_04181, anticorps LOC5565051, anticorps EDI_289460, anticorps CpipJ_CPIJ003334, anticorps EHI_194070, anticorps PTRG_02716, anticorps BDBG_01801, anticorps psmC6, anticorps MCYG_07206, anticorps PITG_00229, anticorps VDBG_04729, anticorps MGYG_04704, anticorps TERG_01608, anticorps DICPUDRAFT_97252, anticorps Tsp_02519, anticorps prs10, anticorps LOC100282100, anticorps Psmc6, anticorps psmc6, anticorps psmc6.L, anticorps PSMC6, anticorps LOC693577, anticorps psmc6.S, anticorps LOC100117671

Sujet: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chromosomes 8 and 12.

Cellular Localization: Cytoplasm (By similarity) , Nucleus

Poids moléculaire: 44 kDa

ID gène: 5706

UniProt: P62333

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway