GPC1 anticorps

N° du produit ABIN2855849

Détail du produit anti-GPC1 anticorps

Antigène: GPC1 (Glypican 1 (GPC1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPC1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Rabbit Polyclonal antibody to Glypican 1 (glypican 1)
Glypican 1 antibody [N3C3]

Purification: Purified by antigen-affinity chromatography.

Classe de qualité: KO Validated

Immunogène: Recombinant protein encompassing a sequence within the center region of human Glypican 1. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. FACS: 1:50-1:200. IP: 1:100-1:500. ELISA: 1:1000-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: MDA-MB-231 , MDA-MB-231 (24 μg/ml Tunicamycin for 16hr) , U87-MG membrane extracts , U87-MG conditioned medium , Mouse brain , mouse fetal brain , A431 , MCF-7 , AsPC-1

Validation: Comparison, KO/KD, Orthogonal

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.58 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-GPC1 (ABIN2855849)

Lu, Niu, Liu, Gao, Sun, Zhao: "Elevated glypican-1 expression is associated with an unfavorable prognosis in pancreatic ductal adenocarcinoma." dans: Cancer medicine, Vol. 6, Issue 6, pp. 1181-1191, (2018) (PubMed).

Huang, Ge, Izzi, Greenspan: "α3 Chains of type V collagen regulate breast tumour growth via glypican-1." dans: Nature communications, Vol. 8, pp. 14351, (2018) (PubMed).

Détails sur GPC1

Antigène: GPC1 (Glypican 1 (GPC1))

Autre désignation: glypican 1 (GPC1 Produits)

Synonymes: anticorps gpc1, anticorps zgc:63947, anticorps GPC1, anticorps Glypican-1, anticorps glypican, anticorps AI462976, anticorps HSPG M12, anticorps HSPGM12, anticorps glypican 1b, anticorps glypican 1, anticorps gpc1b, anticorps GPC1, anticorps gpc1, anticorps Gpc1

Sujet: Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.

Poids moléculaire: 62 kDa

ID gène: 2817

UniProt: P35052

Pathways: Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation