MMP7 anticorps (C-Term)

N° du produit ABIN2855888

Détail du produit anti-MMP7 anticorps

Antigène: MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP7 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Boeuf (Vache), Humain, Souris, Rat

Attributs du produit: Rabbit polyclonal antibody to MMP7 (matrix metallopeptidase 7 (matrilysin, uterine))
MMP7 antibody [C2C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human MMP7. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Validation: Orthogonal

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.45 mg/mL

Buffer: 1XPBS pH 7, 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-MMP7 (ABIN2855888)

Cai, Sun, Duan, Qiu, Dai, Yang, He: "FHL2 promotes tubular epithelial-to-mesenchymal transition through modulating β-catenin signalling." dans: Journal of cellular and molecular medicine, Vol. 22, Issue 3, pp. 1684-1695, (2019) (PubMed).

Luo, Liao, Liao, Chen, Huang, Fan, Liao: "The role of kinesin KIF18A in the invasion and metastasis of hepatocellular carcinoma." dans: World journal of surgical oncology, Vol. 16, Issue 1, pp. 36, (2018) (PubMed).

Oelusarz, Nichols, Grunz-Borgmann, Chen, Akintola, Catania, Burghardt, Trzeciakowski, Parrish: "Overexpression of MMP-7 Increases Collagen 1A2 in the Aging Kidney." dans: Physiological reports, Vol. 1, Issue 5, (2013) (PubMed).

Détails sur MMP7

Antigène: MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))

Autre désignation: matrix metallopeptidase 7 (MMP7 Produits)

Synonymes: anticorps MAT, anticorps MPMM, anticorps MMP-7, anticorps MPSL1, anticorps PUMP-1, anticorps matrilysin, anticorps LOC727698, anticorps MMP7, anticorps Matrilysin, anticorps matrix metallopeptidase 7, anticorps MMP7, anticorps Mmp7

Sujet: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Cellular Localization: Secreted , extracellular space , extracellular matrix

Poids moléculaire: 30 kDa

ID gène: 4316

UniProt: P09237

Pathways: Production of Molecular Mediator of Immune Response