SOCS5 anticorps (N-Term)

N° du produit ABIN2855921

Détail du produit anti-SOCS5 anticorps

Antigène: SOCS5 (Suppressor of Cytokine Signaling 5 (SOCS5))

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOCS5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Rat (Rattus), Porc, Poulet, Macaque rhésus, Boeuf (Vache)

Réactivité croisée (Details): Rat (100 %), Pig (100 %), Chicken (100 %), Rhesus Monkey (100 %), Bovine (100 %)

Attributs du produit: Rabbit Polyclonal antibody to SOCS5 (suppressor of cytokine signaling 5)
SOCS5 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human SOCS5. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Commentaires:

Positive Control: Molt-4 , NT2D1 , PC-3 , mouse testis

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS, 40 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-SOCS5 (ABIN2855921)

Cui, Chen, Zhang, Cheng, Pan, Huang, Hu, Zhang, Wang, Zhu, Chen, Liu, Zhao, Wu, Yang, Liu, Zhang, Yu, Yin, Jing, Rehman, Tian, Pan, Jia: "Duck Tembusu Virus Utilizes miR-221-3p Expression to Facilitate Viral Replication via Targeting of Suppressor of Cytokine Signaling 5." dans: Frontiers in microbiology, Vol. 11, pp. 596, (2020) (PubMed).

Tsai, Kuo, Hung, Wu, Wu, Chang, Kuo, Hsu: "Angpt2 Induces Mesangial Cell Apoptosis through the MicroRNA-33-5p-SOCS5 Loop in Diabetic Nephropathy." dans: Molecular therapy. Nucleic acids, Vol. 13, pp. 543-555, (2018) (PubMed).

Détails sur SOCS5

Antigène: SOCS5 (Suppressor of Cytokine Signaling 5 (SOCS5))

Autre désignation: SOCS5 (SOCS5 Produits)

Synonymes: anticorps SOCS5, anticorps cis6, anticorps cish5, anticorps cish6, anticorps socs-5, anticorps GB18949, anticorps socs5, anticorps zgc:153506, anticorps CIS6, anticorps CISH6, anticorps Cish5, anticorps SOCS-5, anticorps 1810018L08Rik, anticorps mKIAA0671, anticorps RGD1564914, anticorps suppressor of cytokine signaling 5, anticorps suppressor of cytokine signaling 5a, anticorps suppressor of cytokine signaling 5 L homeolog, anticorps SOCS5, anticorps socs5, anticorps LOC552036, anticorps socs5a, anticorps Tsp_07018, anticorps socs5.L, anticorps Socs5

Sujet: The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported.

Poids moléculaire: 61 kDa

ID gène: 9655

Pathways: Signalistation JAK/STAT, EGFR Signaling Pathway, Positive Regulation of Immune Effector Process