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PRKACA anticorps (Center)

PRKACA Reactivité: Humain, Souris WB, IHC (p), IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2855997
  • Antigène Voir toutes PRKACA Anticorps
    PRKACA (Protein Kinase A, alpha (PRKACA))
    Épitope
    • 15
    • 9
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reactivité
    • 52
    • 36
    • 14
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    Humain, Souris
    Hôte
    • 56
    • 9
    • 2
    • 1
    Lapin
    Clonalité
    • 60
    • 8
    Polyclonal
    Conjugué
    • 37
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PRKACA est non-conjugé
    Application
    • 53
    • 30
    • 17
    • 13
    • 13
    • 9
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)
     Réactivité croisée
    Rat (Rattus), Chien, Mouton, Boeuf (Vache)
    Réactivité croisée (Details)
    Rat (100 %), Dog (100 %), Sheep (100 %), Bovine (100 %)
    Attributs du produit
    Rabbit Polyclonal antibody to PKA C alpha (protein kinase, cAMP-dependent, catalytic, alpha)
    PKA C alpha antibody [N2C3]
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Recombinant protein encompassing a sequence within the center region of human PKA C alpha. The exact sequence is proprietary.
    Isotype
    IgG
  • Indications d'application
    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
    Commentaires

    Positive Control: HeLa , Jurkat , NT2D1 , mouse brain

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.38 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Agent conservateur
    Thimerosal (Merthiolate)
    Précaution d'utilisation
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    PRKACA (Protein Kinase A, alpha (PRKACA))
    Autre désignation
    PKA C alpha (PRKACA Produits)
    Synonymes
    anticorps PKACA, anticorps Calpha, anticorps Cs-PKA, anticorps PKCA1, anticorps PKA, anticorps PKCD, anticorps Pkaca, anticorps zgc:158799, anticorps protein kinase cAMP-activated catalytic subunit alpha, anticorps protein kinase, cAMP dependent, catalytic, alpha, anticorps cAMP-dependent protein kinase catalytic subunit, anticorps protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a, anticorps PRKACA, anticorps Prkaca, anticorps kin-1, anticorps prkacaa
    Sujet
    CAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

    Cellular Localization: Cytoplasm (By similarity) , Nucleus (By similarity)
    Poids moléculaire
    41 kDa
    ID gène
    5566
    Pathways
    Signalisation NF-kappaB, Signalisation Hedgehog, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Carbohydrate Homeostasis, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, Lipid Metabolism, SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2
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