MAPKAP Kinase 3 anticorps
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- Antigène Voir toutes MAPKAP Kinase 3 (MAPKAPK3) Anticorps
- MAPKAP Kinase 3 (MAPKAPK3) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MAPKAP Kinase 3 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Réactivité croisée
- Humain, Souris
- Attributs du produit
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Rabbit Polyclonal antibody to MAPKAP Kinase 3 (mitogen-activated protein kinase-activated protein kinase 3)
MAPKAP Kinase 3 antibody [N2C3] - Purification
- Purified by antigen-affinity chromatography.
- Classe de qualité
- KO Validated
- Immunogène
- Recombinant protein encompassing a sequence within the center region of human MAPKAP Kinase 3. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product MAPKAPK3 Anticorps primaire
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- Indications d'application
- WB: 1:500-1:20000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Commentaires
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Positive Control: Mouse spleen , H1299 , HeLaS3 , HeLa
Validation: KO/KD
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- Agent conservateur
- Thimerosal (Merthiolate)
- Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Antigène
- MAPKAP Kinase 3 (MAPKAPK3) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3))
- Autre désignation
- mitogen-activated protein kinase-activated protein kinase 3 (MAPKAPK3 Produits)
- Synonymes
- anticorps 3PK, anticorps MAPKAP-K3, anticorps MAPKAP3, anticorps MAPKAPK-3, anticorps MK-3, anticorps AI874665, anticorps MK3, anticorps MapkKapk3, anticorps MAPKAPK3, anticorps mapkapk3, anticorps MGC154360, anticorps 3pk, anticorps mapkap3, anticorps zgc:158342, anticorps mitogen-activated protein kinase-activated protein kinase 3, anticorps mitogen-activated protein kinase-activated protein kinase 3 S homeolog, anticorps MAPKAPK3, anticorps Mapkapk3, anticorps mapkapk3.S, anticorps mapkapk3
- Sujet
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This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation.
Cellular Localization: Nucleus , Cytoplasm - Poids moléculaire
- 43 kDa
- ID gène
- 7867
- UniProt
- Q16644
- Pathways
- Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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