PPP1CA anticorps (Center)
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- Antigène Voir toutes PPP1CA Anticorps
- PPP1CA (Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA))
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Épitope
- Center
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Reactivité
- Humain, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PPP1CA est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Réactivité croisée
- Boeuf (Vache), Souris
- Réactivité croisée (Details)
- Mouse (100 %), Bovine (100 %)
- Attributs du produit
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Rabbit Polyclonal antibody to PPP1A (protein phosphatase 1, catalytic subunit, alpha isozyme)
PPP1A antibody - Purification
- Purified by antigen-affinity chromatography.
- Immunogène
- Recombinant protein encompassing a sequence within the center region of human PPP1A. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product PPP1CA Anticorps primaire
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- Indications d'application
- Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
- Commentaires
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Positive Control: 293T , A431 , rat brain
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.58 mg/mL
- Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- Agent conservateur
- Thimerosal (Merthiolate)
- Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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Phosphorylation of the Ndc80 complex protein, HEC1, by Nek2 kinase modulates chromosome alignment and signaling of the spindle assembly checkpoint." dans: Molecular biology of the cell, Vol. 22, Issue 19, pp. 3584-94, (2012) (PubMed).
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Phosphorylation of the Ndc80 complex protein, HEC1, by Nek2 kinase modulates chromosome alignment and signaling of the spindle assembly checkpoint." dans: Molecular biology of the cell, Vol. 22, Issue 19, pp. 3584-94, (2012) (PubMed).
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- Antigène
- PPP1CA (Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA))
- Autre désignation
- PPP1A (PPP1CA Produits)
- Synonymes
- anticorps PP-1A, anticorps PP1A, anticorps PP1alpha, anticorps PPP1A, anticorps Ppp1c, anticorps dism2, anticorps ppp1a, anticorps wu:fc04c08, anticorps wu:fc09b07, anticorps wu:fc30g11, anticorps wu:fe05h08, anticorps zgc:85729, anticorps Ppp1ca, anticorps fb18b03, anticorps fd20h04, anticorps wu:fb18b03, anticorps wu:fd20h04, anticorps wu:fl22a03, anticorps zgc:55744, anticorps zgc:76940, anticorps protein phosphatase 1 catalytic subunit alpha, anticorps protein phosphatase 1, catalytic subunit, alpha isoform, anticorps protein phosphatase 1, catalytic subunit, alpha isozyme L homeolog, anticorps protein phosphatase 1, catalytic subunit, alpha isozyme, anticorps protein phosphatase 1, catalytic subunit, alpha isozyme a, anticorps protein phosphatase 1, catalytic subunit, alpha isozyme b, anticorps PPP1CA, anticorps Ppp1ca, anticorps ppp1ca.L, anticorps ppp1ca, anticorps ppp1caa, anticorps ppp1cab
- Sujet
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The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Cellular Localization: Cytoplasm - Poids moléculaire
- 38 kDa
- ID gène
- 5499
- Pathways
- M Phase, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Lipid Metabolism
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