ERCC2 anticorps (Internal Region)
-
- Antigène Voir toutes ERCC2 Anticorps
- ERCC2 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2 (ERCC2))
-
Épitope
- Internal Region
-
Reactivité
- Humain, Souris
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp ERCC2 est non-conjugé
-
Application
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Réactivité croisée
- Chimpanzé
- Réactivité croisée (Details)
- Chimpanzee (100 %)
- Attributs du produit
-
Rabbit Polyclonal antibody to ERCC2 (excision repair cross-complementing rodent repair deficiency, complementation group 2)
ERCC2 antibody [N2C2], Internal - Purification
- Purified by antigen-affinity chromatography.
- Immunogène
- Recombinant protein encompassing a sequence within the center region of human ERCC2. The exact sequence is proprietary.
- Isotype
- IgG
-
-
- Indications d'application
- Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
- Commentaires
-
Positive Control: IMR32 , U87-MG
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- 1XPBS, 1 % BSA, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- Agent conservateur
- Thimerosal (Merthiolate)
- Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
- Antigène
- ERCC2 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2 (ERCC2))
- Autre désignation
- ERCC2 (ERCC2 Produits)
- Synonymes
- anticorps COFS2, anticorps EM9, anticorps TTD, anticorps XPD, anticorps AA407812, anticorps AU020867, anticorps AW240756, anticorps CXPD, anticorps Ercc-2, anticorps MGC89573, anticorps CG9433, anticorps DhR3, anticorps DhXPD, anticorps DmXPD, anticorps Dmel\\CG9433, anticorps ERCC2, anticorps XPD/ERCC2, anticorps l(2)SH2 2137, anticorps l(2)SH2137, anticorps xpd, anticorps zgc:56365, anticorps ERCC excision repair 2, TFIIH core complex helicase subunit, anticorps excision repair cross-complementing rodent repair deficiency, complementation group 2, anticorps excision repair cross-complementation group 2, anticorps Xeroderma pigmentosum D, anticorps ERCC2, anticorps Ercc2, anticorps ercc2, anticorps Xpd
- Sujet
-
The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Cellular Localization: Nucleus - Poids moléculaire
- 87 kDa
- ID gène
- 2068
- Pathways
- Réparation de l'ADN
-