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GSTa2 anticorps

GSTa2 Reactivité: Humain WB, ICC, IHC (p), IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2856132
  • Antigène Voir toutes GSTa2 Anticorps
    GSTa2 (Glutathione S-Transferase alpha 2 (GSTa2))
    Reactivité
    • 38
    • 3
    • 1
    Humain
    Hôte
    • 35
    • 4
    Lapin
    Clonalité
    • 37
    • 2
    Polyclonal
    Conjugué
    • 18
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GSTa2 est non-conjugé
    Application
    • 32
    • 24
    • 18
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Specificité
    This antibody was raised against human GSTA2 antibody. It is able to detect GSTA1, GSTA2, and GSTA3 proteins but not cross reacts with GSTA4 or GSTA5 proteins based on customer's feedback.
     Réactivité croisée
    Humain, Rat
    Attributs du produit
    Rabbit Polyclonal antibody to GSTA2 (glutathione S-transferase alpha 2)
    GSTA2 antibody [N1C3]
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Recombinant protein encompassing a sequence within the center region of human GSTA2. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product GSTa2 Anticorps primaire
  • Indications d'application
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Commentaires

    Positive Control: HepG2

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Agent conservateur
    Thimerosal (Merthiolate)
    Précaution d'utilisation
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    GSTa2 (Glutathione S-Transferase alpha 2 (GSTa2))
    Autre désignation
    glutathione S-transferase alpha 2 (GSTa2 Produits)
    Synonymes
    anticorps GSTA1, anticorps GST2, anticorps GSTA2-2, anticorps GTA2, anticorps GTH2, anticorps Gsta1, anticorps Gst2-2, anticorps Gstc-2, anticorps Gstc2, anticorps glutathione S-transferase alpha 2, anticorps glutathione S-transferase, anticorps glutathione S-transferase, alpha 2 (Yc2), anticorps GSTA2, anticorps Gsta2
    Sujet
    Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.

    Cellular Localization: Cytoplasm
    Poids moléculaire
    26 kDa
    ID gène
    2939
    UniProt
    P09210
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