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MBD2 anticorps (Center)

MBD2 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2856140
  • Antigène Voir toutes MBD2 Anticorps
    MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
    Épitope
    • 9
    • 8
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reactivité
    • 47
    • 23
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 44
    • 2
    • 1
    Lapin
    Clonalité
    • 44
    • 3
    Polyclonal
    Conjugué
    • 25
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MBD2 est non-conjugé
    Application
    • 40
    • 22
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
     Réactivité croisée
    Souris, Rat (Rattus), Xenopus laevis
    Réactivité croisée (Details)
    Mouse (98 %), Rat (98 %), Xenopus laevis (89 %)
    Attributs du produit
    Rabbit polyclonal antibody to MBD2 (methyl-CpG binding domain protein 2)
    MBD2 antibody [N2C3]
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Recombinant protein encompassing a sequence within the center region of human MBD2. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product MBD2 Anticorps primaire
  • Indications d'application
    Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
    Commentaires

    Positive Control: A431 , Jurkat , Raji

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.48 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Agent conservateur
    Thimerosal (Merthiolate)
    Précaution d'utilisation
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
    Autre désignation
    MBD2 (MBD2 Produits)
    Synonymes
    anticorps MBD2, anticorps DMTase, anticorps NY-CO-41, anticorps MBD2a, anticorps wu:fa97f06, anticorps zgc:111862, anticorps methyl-CpG binding domain protein 2, anticorps methyl-CpG binding domain protein 2 S homeolog, anticorps MBD2, anticorps Mbd2, anticorps mbd2, anticorps mbd2.S
    Sujet
    DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal. It is also reported that the this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing.

    Cellular Localization: Nucleus
    Poids moléculaire
    43 kDa
    ID gène
    8932
    Pathways
    Chromatin Binding
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