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DCLK2 anticorps

DCLK2 Reactivité: Humain WB, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2856229
  • Antigène Voir toutes DCLK2 Anticorps
    DCLK2 (Doublecortin-Like Kinase 2 (DCLK2))
    Reactivité
    • 32
    • 13
    • 3
    Humain
    Hôte
    • 30
    • 2
    Lapin
    Clonalité
    • 30
    • 2
    Polyclonal
    Conjugué
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DCLK2 est non-conjugé
    Application
    • 24
    • 19
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
     Réactivité croisée
    Humain
    Attributs du produit
    Rabbit polyclonal antibody to DCAMKL2 (doublecortin-like kinase 2)
    DCAMKL2 antibody [N2C2], Internal
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Recombinant protein encompassing a sequence within the center region of human DCAMKL2. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product DCLK2 Anticorps primaire
  • Indications d'application
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Commentaires

    Positive Control: A549 , H1299 , HCT116

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.16 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Agent conservateur
    Thimerosal (Merthiolate)
    Précaution d'utilisation
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    DCLK2 (Doublecortin-Like Kinase 2 (DCLK2))
    Autre désignation
    doublecortin like kinase 2 (DCLK2 Produits)
    Synonymes
    anticorps CL2, anticorps CLICK-II, anticorps CLICK2, anticorps CLIK2, anticorps DCAMKL2, anticorps DCDC3, anticorps DCDC3B, anticorps DCK2, anticorps 6330415M09Rik, anticorps AU044875, anticorps Click-II, anticorps Dcamkl2, anticorps DCLK2, anticorps cb572, anticorps dclk, anticorps sb:cb572, anticorps si:dkey-180n16.1, anticorps Dck2, anticorps RGD1308384, anticorps doublecortin like kinase 2, anticorps doublecortin-like kinase 2, anticorps doublecortin-like kinase 2a, anticorps DCLK2, anticorps Dclk2, anticorps dclk2a
    Sujet
    This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. Mouse studies show that the DCX gene, another family member, and this gene share function in the establishment of hippocampal organization and that their absence results in a severe epileptic phenotype and lethality, as described in human patients with lissencephaly. Multiple alternatively spliced transcript variants have been identified.

    Poids moléculaire
    84 kDa
    ID gène
    166614
    UniProt
    Q8N568
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