RAD21 anticorps (Center)

N° du produit ABIN2856242

Détail du produit anti-RAD21 anticorps

Antigène: RAD21 (RAD21 Homolog (RAD21))

Épitope: Center

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD21 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Attributs du produit: Rabbit Polyclonal antibody to RAD21 (RAD21 homolog (S. pombe))
RAD21 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human RAD21. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Immunoprecipitation 1:100-1:500* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Immunoprecipitation1:100-1:500* Western blot1:500-1:3000*

Commentaires:

Positive Control: K562 , THP-1 , HL-60 , NIH-3T3 , JC , BCL-1

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS, 20 % Glycerol ( pH 7). 0.025 % ProClin 300 was added as a preservative.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-RAD21 (ABIN2856242)

Ochiai, Hayashi, Umeda, Yoshimura, Harada, Shimizu, Nakano, Saitoh, Liu, Yamamoto, Okamura, Ohkawa, Kimura, Nikaido: "Genome-wide kinetic properties of transcriptional bursting in mouse embryonic stem cells." dans: Science advances, Vol. 6, Issue 25, pp. eaaz6699, (2020) (PubMed).

Détails sur RAD21

Antigène: RAD21 (RAD21 Homolog (RAD21))

Autre désignation: RAD21 (RAD21 Produits)

Synonymes: anticorps rad21, anticorps wu:fb55d02, anticorps wu:fb93f04, anticorps CDLS4, anticorps HR21, anticorps HRAD21, anticorps MCD1, anticorps NXP1, anticorps SCC1, anticorps hHR21, anticorps mKIAA0078, anticorps hr21, anticorps mcd1, anticorps nxp-1, anticorps nxp1, anticorps scc1, anticorps xrad21, anticorps RAD21 cohesin complex component, anticorps RAD21 cohesin complex component a, anticorps RAD21 cohesin complex component L homeolog, anticorps RAD21 cohesin complex component S homeolog, anticorps R-spondin 2, anticorps RAD21, anticorps rad21a, anticorps rad21.L, anticorps Rad21, anticorps rad21.S, anticorps RSPO2

Sujet: The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells.

Cellular Localization: Nucleus

Poids moléculaire: 72 kDa

ID gène: 5885

Pathways: Positive Regulation of Endopeptidase Activity